This is a simulated dataset from Wang2007 where various NONMEM estimation methods (Laplace FO, FOCE with and without interaction) are described.

Wang2007

Format

A data frame with 20 rows and 3 columns

ID

Simulated Subject ID

Time

Simulated Time

Y

Simulated Value

Source

Table 1 from Wang, Y Derivation of Various NONMEM estimation methods. J Pharmacokinet Pharmacodyn (2007) 34:575-593.

See also