Augmented Prediction for nlmixr fit
Nlmixr fit object
some methods for the generic may require additional arguments.
specifies the interpolation method for
time-varying covariates. When solving ODEs it often samples
times outside the sampling time specified in events
.
When this happens, the time varying covariates are
interpolated. Currently this can be:
"linear"
interpolation, which interpolates the covariate
by solving the line between the observed covariates and extrapolating the new
covariate value.
"constant"
-- Last observation carried forward (the default).
"NOCB"
-- Next Observation Carried Backward. This is the same method
that NONMEM uses.
"midpoint"
Last observation carried forward to midpoint; Next observation
carried backward to midpoint.
an optional one-sided formula specifying the primary
covariate to be used to generate the augmented predictions. By
default, if a covariate can be extracted from the data used to generate
object
(using getCovariate
), it will be used as
primary
.
an optional lower limit for the primary
covariate. Defaults to min(primary)
.
an optional upper limit for the primary
covariate. Defaults to max(primary)
.
an optional integer with the number of primary covariate values at which to evaluate the predictions. Defaults to 51.
Stacked data.frame with observations, individual/population predictions.