Fit a non-population dynamic model

dynmodel(
  system,
  model,
  inits,
  data,
  fixPars = NULL,
  nlmixrObject = NULL,
  control = list(),
  ...
)

Arguments

system

RxODE object. See RxODE for more details.

model

Error model.

inits

Initial values of system parameters.

data

Dataset to estimate. Needs to be RxODE compatible in EVIDs.

fixPars

Fixed system parameters. Default is NULL.

nlmixrObject

nlmixr object. See nlmixr for more details. Default is NULL.

control

Control options for dynmodel dynmodelControl .

...

Other parameters (ignored)

Value

A dynmodel fit object

Author

Wenping Wang, Mason McComb and Matt Fidler

Examples


# \donttest{

# dynmodel example --------------------------------------------------------
ode <- "
      kel = CL/V;
      d/dt(X) = -kel*X;
      C=X/V;
      PRED = C
      "
ode_system <- RxODE(model = ode)
#>  
model_error_structure <- cp ~ C + add(0.01) + prop(0.01)
inits <- c(CL = 1, V = 10)
control <- dynmodelControl(method = "Nelder-Mead")
fit <-
  try(dynmodel(
    system = ode_system,
    model = model_error_structure,
    data = Bolus_1CPT,
    inits = inits,
    control = control
  ))
#> |-----+---------------+-----------+-----------+-----------+-----------|
#> |    #| Objective Fun |        CL |         V |       add |      prop |
#> |    1|     1487008.6 |     1.000 |     10.00 |   0.01000 |   0.01000 |
#> |    U|     1487008.6 |     1.000 |     10.00 |   0.01000 |   0.01000 |
#> |    2|     1487008.6 |    0.8000 |     10.00 |   0.01000 |   0.01000 |
#> |    U|     1487008.6 |    0.8000 |     10.00 |   0.01000 |   0.01000 |
#> |    3|     1487008.6 |     1.000 |     8.000 |   0.01000 |   0.01000 |
#> |    U|     1487008.6 |     1.000 |     8.000 |   0.01000 |   0.01000 |
#> |    4|     1493743.8 |     1.000 |     10.00 |  0.008000 |   0.01000 |
#> |    U|     1493743.8 |     1.000 |     10.00 |  0.008000 |   0.01000 |
#> |    5|     2302237.1 |     1.000 |     10.00 |   0.01000 |  0.008000 |
#> |    U|     2302237.1 |     1.000 |     10.00 |   0.01000 |  0.008000 |
#> |    6|     1043965.3 |    0.9000 |     9.000 |  0.009000 |   0.01200 |
#> |    U|     1043965.3 |    0.9000 |     9.000 |  0.009000 |   0.01200 |
#> |    7|     774746.27 |    0.8500 |     8.500 |  0.008500 |   0.01400 |
#> |    U|     774746.27 |    0.8500 |     8.500 |  0.008500 |   0.01400 |
#> |    8|     1039469.2 |    0.8250 |     8.250 |   0.01125 |   0.01200 |
#> |    U|     1039469.2 |    0.8250 |     8.250 |   0.01125 |   0.01200 |
#> |    9|     892071.79 |     1.037 |     7.375 |  0.009875 |   0.01300 |
#> |    U|     892071.79 |     1.037 |     7.375 |  0.009875 |   0.01300 |
#> |   10|     722274.73 |    0.8562 |     9.062 |  0.009813 |   0.01450 |
#> |    U|     722274.73 |    0.8562 |     9.062 |  0.009813 |   0.01450 |
#> |   11|     547640.04 |    0.7844 |     9.594 |  0.009719 |   0.01675 |
#> |    U|     547640.04 |    0.7844 |     9.594 |  0.009719 |   0.01675 |
#> |   12|     483911.36 |    0.7484 |     6.859 |  0.009672 |   0.01787 |
#> |    U|     483911.36 |    0.7484 |     6.859 |  0.009672 |   0.01787 |
#> |   13|     333073.34 |    0.6227 |     5.289 |  0.009508 |   0.02181 |
#> |    U|     333073.34 |    0.6227 |     5.289 |  0.009508 |   0.02181 |
#> |   14|     365491.93 |    0.8223 |     7.129 |  0.007551 |   0.02078 |
#> |    U|     365491.93 |    0.8223 |     7.129 |  0.007551 |   0.02078 |
#> |   15|     287159.92 |    0.5021 |     7.881 |  0.007764 |   0.02367 |
#> |    U|     287159.92 |    0.5021 |     7.881 |  0.007764 |   0.02367 |
#> |   16|     199785.52 |    0.2345 |     8.134 |  0.006708 |   0.02901 |
#> |    U|     199785.52 |    0.2345 |     8.134 |  0.006708 |   0.02901 |
#> |   17|     186206.44 |    0.3819 |     6.573 |  0.008243 |   0.03018 |
#> |    U|     186206.44 |    0.3819 |     6.573 |  0.008243 |   0.03018 |
#> |   18|     125691.57 |    0.1478 |     5.609 |  0.008114 |   0.03826 |
#> |    U|     125691.57 |    0.1478 |     5.609 |  0.008114 |   0.03826 |
#> |   19|     126339.01 |    0.1292 |     3.487 |  0.006222 |   0.03818 |
#> |    U|     126339.01 |    0.1292 |     3.487 |  0.006222 |   0.03818 |
#> |   20|     105729.15 |   -0.2552 |     4.130 |  0.007725 |   0.04285 |
#> |    U|     105729.15 |   -0.2552 |     4.130 |  0.007725 |   0.04285 |
#> |   21|     77192.666 |   -0.7939 |     2.631 |  0.007812 |   0.05389 |
#> |    U|     77192.666 |   -0.7939 |     2.631 |  0.007812 |   0.05389 |
#> |   22|     70930.129 |   -0.7638 |     4.641 |  0.004920 |   0.05786 |
#> |    U|     70930.129 |   -0.7638 |     4.641 |  0.004920 |   0.05786 |
#> |   23|     53932.881 |    -1.457 |     4.317 |  0.002626 |   0.07588 |
#> |    U|     53932.881 |    -1.457 |     4.317 |  0.002626 |   0.07588 |
#> |   24|     54975.876 |    -1.221 |   -0.1115 |  0.005679 |   0.07410 |
#> |    U|     54975.876 |    -1.221 |   -0.1115 |  0.005679 |   0.07410 |
#> |   25|     50213.136 |    -1.792 |     2.736 |  0.005894 |   0.08288 |
#> |    U|     50213.136 |    -1.792 |     2.736 |  0.005894 |   0.08288 |
#> |   26|     43493.772 |    -2.752 |     2.361 |  0.005730 |    0.1052 |
#> |    U|     43493.772 |    -2.752 |     2.361 |  0.005730 |    0.1052 |
#> |   27|     41723.672 |    -3.260 |    -1.010 |  0.002809 |    0.1163 |
#> |    U|     41723.672 |    -3.260 |    -1.010 |  0.002809 |    0.1163 |
#> |   28|     38792.534 |    -4.964 |    -4.319 | 0.0001571 |    0.1553 |
#> |    U|     38792.534 |    -4.964 |    -4.319 | 0.0001571 |    0.1553 |
#> |   29|     38945.709 |    -4.403 |    -1.507 |-0.0007160 |    0.1514 |
#> |    U|     38945.709 |    -4.403 |    -1.507 |-0.0007160 |    0.1514 |
#> |   30|     38374.346 |    -5.567 |    0.5376 | -0.001780 |    0.1698 |
#> |    U|     38374.346 |    -5.567 |    0.5376 | -0.001780 |    0.1698 |
#> |   31|     38027.291 |    -7.739 |    0.8621 | -0.005510 |    0.2176 |
#> |    U|     38027.291 |    -7.739 |    0.8621 | -0.005510 |    0.2176 |
#> |   32|     38128.019 |    -8.472 |    -5.619 | -0.002795 |    0.2389 |
#> |    U|     38128.019 |    -8.472 |    -5.619 | -0.002795 |    0.2389 |
#> |   33|     38466.546 |    -10.04 |    -7.653 |  -0.01016 |    0.2764 |
#> |    U|     38466.546 |    -10.04 |    -7.653 |  -0.01016 |    0.2764 |
#> |   34|     38649.017 |    -11.20 |    -6.857 | -0.008439 |    0.2927 |
#> |    U|     38649.017 |    -11.20 |    -6.857 | -0.008439 |    0.2927 |
#> |   35|     39454.074 |    -13.76 |    -5.314 |  -0.01361 |    0.3575 |
#> |    U|     39454.074 |    -13.76 |    -5.314 |  -0.01361 |    0.3575 |
#> |   36|     38020.121 |    -7.163 |    -4.568 | -0.003285 |    0.2059 |
#> |    U|     38020.121 |    -7.163 |    -4.568 | -0.003285 |    0.2059 |
#> |   37|     38245.755 |    -5.503 |    -1.632 | -0.002437 |    0.1766 |
#> |    U|     38245.755 |    -5.503 |    -1.632 | -0.002437 |    0.1766 |
#> |   38|     39336.269 |    -4.402 |     2.175 |  0.003149 |    0.1431 |
#> |    U|     39336.269 |    -4.402 |     2.175 |  0.003149 |    0.1431 |
#> |   39|     38157.426 |    -8.628 |    -5.196 | -0.006834 |    0.2431 |
#> |    U|     38157.426 |    -8.628 |    -5.196 | -0.006834 |    0.2431 |
#> |   40|     38462.561 |    -10.50 |    -5.629 | -0.006775 |    0.2761 |
#> |    U|     38462.561 |    -10.50 |    -5.629 | -0.006775 |    0.2761 |
#> |   41|     38028.571 |    -6.752 |    -2.631 | -0.003521 |    0.2015 |
#> |    U|     38028.571 |    -6.752 |    -2.631 | -0.003521 |    0.2015 |
#> |   42|     38100.333 |    -6.435 |   -0.7819 |-0.0007213 |    0.1889 |
#> |    U|     38100.333 |    -6.435 |   -0.7819 |-0.0007213 |    0.1889 |
#> |   43|     38409.707 |    -5.573 |     2.060 | -0.003723 |    0.1680 |
#> |    U|     38409.707 |    -5.573 |     2.060 | -0.003723 |    0.1680 |
#> |   44|     38037.842 |    -7.747 |    -3.699 | -0.003027 |    0.2212 |
#> |    U|     38037.842 |    -7.747 |    -3.699 | -0.003027 |    0.2212 |
#> |   45|     38098.156 |    -8.266 |    -4.236 | -0.006950 |    0.2342 |
#> |    U|     38098.156 |    -8.266 |    -4.236 | -0.006950 |    0.2342 |
#> |   46|     38043.181 |    -7.808 |    -3.373 | -0.005393 |    0.2229 |
#> |    U|     38043.181 |    -7.808 |    -3.373 | -0.005393 |    0.2229 |
#> |   47|     38033.280 |    -6.893 |    -1.645 | -0.002279 |    0.2002 |
#> |    U|     38033.280 |    -6.893 |    -1.645 | -0.002279 |    0.2002 |
#> |   48|     38077.121 |    -6.526 |   -0.2918 | -0.004270 |    0.1914 |
#> |    U|     38077.121 |    -6.526 |   -0.2918 | -0.004270 |    0.1914 |
#> |   49|     38020.744 |    -7.442 |    -2.848 | -0.003338 |    0.2137 |
#> |    U|     38020.744 |    -7.442 |    -2.848 | -0.003338 |    0.2137 |
#> |   50|     38031.184 |    -7.656 |    -2.947 | -0.005548 |    0.2192 |
#> |    U|     38031.184 |    -7.656 |    -2.947 | -0.005548 |    0.2192 |
#> |   51|     38021.231 |    -7.465 |    -2.621 | -0.004731 |    0.2144 |
#> |    U|     38021.231 |    -7.465 |    -2.621 | -0.004731 |    0.2144 |
#> |   52|     38048.786 |    -8.153 |    -1.957 | -0.004910 |    0.2243 |
#> |    U|     38048.786 |    -8.153 |    -1.957 | -0.004910 |    0.2243 |
#> |   53|     38018.540 |    -7.102 |    -2.462 | -0.003869 |    0.2072 |
#> |    U|     38018.540 |    -7.102 |    -2.462 | -0.003869 |    0.2072 |
#> |   54|     38025.751 |    -6.847 |    -7.112 | -0.002101 |    0.2030 |
#> |    U|     38025.751 |    -6.847 |    -7.112 | -0.002101 |    0.2030 |
#> |   55|     38019.452 |    -7.070 |    -5.118 | -0.002953 |    0.2066 |
#> |    U|     38019.452 |    -7.070 |    -5.118 | -0.002953 |    0.2066 |
#> |   56|     38027.420 |    -6.924 |    -4.877 | -0.001991 |    0.2023 |
#> |    U|     38027.420 |    -6.924 |    -4.877 | -0.001991 |    0.2023 |
#> |   57|     38018.257 |    -7.330 |    -3.185 | -0.004046 |    0.2114 |
#> |    U|     38018.257 |    -7.330 |    -3.185 | -0.004046 |    0.2114 |
#> |   58|     38027.633 |    -6.891 |    -4.820 | -0.003738 |    0.2018 |
#> |    U|     38027.633 |    -6.891 |    -4.820 | -0.003738 |    0.2018 |
#> |   59|     38018.175 |    -7.304 |    -3.341 | -0.003438 |    0.2108 |
#> |    U|     38018.175 |    -7.304 |    -3.341 | -0.003438 |    0.2108 |
#> |   60|     38018.862 |    -7.240 |    -2.485 | -0.003868 |    0.2121 |
#> |    U|     38018.862 |    -7.240 |    -2.485 | -0.003868 |    0.2121 |
#> |   61|     38020.804 |    -7.418 |   -0.6183 | -0.004657 |    0.2141 |
#> |    U|     38020.804 |    -7.418 |   -0.6183 | -0.004657 |    0.2141 |
#> |   62|     38018.089 |    -7.157 |    -3.993 | -0.003379 |    0.2085 |
#> |    U|     38018.089 |    -7.157 |    -3.993 | -0.003379 |    0.2085 |
#> |   63|     38019.049 |    -7.207 |    -4.006 | -0.003498 |    0.2068 |
#> |    U|     38019.049 |    -7.207 |    -4.006 | -0.003498 |    0.2068 |
#> |   64|     38018.059 |    -7.231 |    -2.865 | -0.003776 |    0.2108 |
#> |    U|     38018.059 |    -7.231 |    -2.865 | -0.003776 |    0.2108 |
#> |   65|     38020.426 |    -7.409 |    -4.230 | -0.003451 |    0.2135 |
#> |    U|     38020.426 |    -7.409 |    -4.230 | -0.003451 |    0.2135 |
#> |   66|     38017.847 |    -7.179 |    -2.904 | -0.003764 |    0.2088 |
#> |    U|     38017.847 |    -7.179 |    -2.904 | -0.003764 |    0.2088 |
#> |   67|     38018.385 |    -7.106 |    -3.366 | -0.003133 |    0.2080 |
#> |    U|     38018.385 |    -7.106 |    -3.366 | -0.003133 |    0.2080 |
#> |   68|     38017.946 |    -7.274 |    -3.231 | -0.003818 |    0.2106 |
#> |    U|     38017.946 |    -7.274 |    -3.231 | -0.003818 |    0.2106 |
#> |   69|     38017.830 |    -7.116 |    -3.156 | -0.003930 |    0.2086 |
#> |    U|     38017.830 |    -7.116 |    -3.156 | -0.003930 |    0.2086 |
#> |   70|     38018.225 |    -7.022 |    -3.064 | -0.004177 |    0.2075 |
#> |    U|     38018.225 |    -7.022 |    -3.064 | -0.004177 |    0.2075 |
#> |   71|     38017.893 |    -7.243 |    -2.085 | -0.004265 |    0.2108 |
#> |    U|     38017.893 |    -7.243 |    -2.085 | -0.004265 |    0.2108 |
#> |   72|     38017.753 |    -7.175 |    -2.823 | -0.004113 |    0.2086 |
#> |    U|     38017.753 |    -7.175 |    -2.823 | -0.004113 |    0.2086 |
#> |   73|     38018.191 |    -7.146 |    -2.801 | -0.004281 |    0.2075 |
#> |    U|     38018.191 |    -7.146 |    -2.801 | -0.004281 |    0.2075 |
#> |   74|     38017.999 |    -7.083 |    -2.253 | -0.004218 |    0.2078 |
#> |    U|     38017.999 |    -7.083 |    -2.253 | -0.004218 |    0.2078 |
#> |   75|     38017.743 |    -7.226 |    -2.986 | -0.003918 |    0.2099 |
#> |    U|     38017.743 |    -7.226 |    -2.986 | -0.003918 |    0.2099 |
#> |   76|     38018.782 |    -7.105 |    -3.850 | -0.003598 |    0.2071 |
#> |    U|     38018.782 |    -7.105 |    -3.850 | -0.003598 |    0.2071 |
#> |   77|     38017.676 |    -7.209 |    -2.526 | -0.004098 |    0.2099 |
#> |    U|     38017.676 |    -7.209 |    -2.526 | -0.004098 |    0.2099 |
#> |   78|     38017.585 |    -7.184 |    -2.841 | -0.004265 |    0.2097 |
#> |    U|     38017.585 |    -7.184 |    -2.841 | -0.004265 |    0.2097 |
#> |   79|     38017.557 |    -7.186 |    -2.810 | -0.004516 |    0.2101 |
#> |    U|     38017.557 |    -7.186 |    -2.810 | -0.004516 |    0.2101 |
#> |   80|     38017.769 |    -7.281 |    -2.416 | -0.004392 |    0.2107 |
#> |    U|     38017.769 |    -7.281 |    -2.416 | -0.004392 |    0.2107 |
#> |   81|     38017.651 |    -7.240 |    -2.601 | -0.004276 |    0.2101 |
#> |    U|     38017.651 |    -7.240 |    -2.601 | -0.004276 |    0.2101 |
#> |   82|     38018.198 |    -7.256 |    -2.639 | -0.004291 |    0.2114 |
#> |    U|     38018.198 |    -7.256 |    -2.639 | -0.004291 |    0.2114 |
#> |   83|     38017.621 |    -7.195 |    -2.777 | -0.004157 |    0.2093 |
#> |    U|     38017.621 |    -7.195 |    -2.777 | -0.004157 |    0.2093 |
#> |   84|     38017.477 |    -7.189 |    -2.371 | -0.004606 |    0.2098 |
#> |    U|     38017.477 |    -7.189 |    -2.371 | -0.004606 |    0.2098 |
#> |   85|     38017.353 |    -7.171 |    -2.063 | -0.004950 |    0.2098 |
#> |    U|     38017.353 |    -7.171 |    -2.063 | -0.004950 |    0.2098 |
#> |   86|     38017.381 |    -7.188 |    -2.599 | -0.004852 |    0.2098 |
#> |    U|     38017.381 |    -7.188 |    -2.599 | -0.004852 |    0.2098 |
#> |   87|     38017.318 |    -7.130 |    -2.523 | -0.004961 |    0.2094 |
#> |    U|     38017.318 |    -7.130 |    -2.523 | -0.004961 |    0.2094 |
#> |   88|     38017.223 |    -7.074 |    -2.484 | -0.005304 |    0.2090 |
#> |    U|     38017.223 |    -7.074 |    -2.484 | -0.005304 |    0.2090 |
#> |   89|     38017.165 |    -7.114 |    -2.201 | -0.005653 |    0.2101 |
#> |    U|     38017.165 |    -7.114 |    -2.201 | -0.005653 |    0.2101 |
#> |   90|     38017.060 |    -7.074 |    -1.914 | -0.006401 |    0.2105 |
#> |    U|     38017.060 |    -7.074 |    -1.914 | -0.006401 |    0.2105 |
#> |   91|     38016.905 |    -7.067 |    -1.720 | -0.006238 |    0.2094 |
#> |    U|     38016.905 |    -7.067 |    -1.720 | -0.006238 |    0.2094 |
#> |   92|     38016.670 |    -7.007 |    -1.175 | -0.007098 |    0.2091 |
#> |    U|     38016.670 |    -7.007 |    -1.175 | -0.007098 |    0.2091 |
#> |   93|     38016.684 |    -6.976 |    -1.219 | -0.007025 |    0.2094 |
#> |    U|     38016.684 |    -6.976 |    -1.219 | -0.007025 |    0.2094 |
#> |   94|     38016.452 |    -6.895 |    -1.333 | -0.007964 |    0.2091 |
#> |    U|     38016.452 |    -6.895 |    -1.333 | -0.007964 |    0.2091 |
#> |   95|     38016.166 |    -6.757 |   -0.9678 | -0.009471 |    0.2088 |
#> |    U|     38016.166 |    -6.757 |   -0.9678 | -0.009471 |    0.2088 |
#> |   96|     38016.174 |    -6.833 |   -0.1534 | -0.009694 |    0.2099 |
#> |    U|     38016.174 |    -6.833 |   -0.1534 | -0.009694 |    0.2099 |
#> |   97|     38016.187 |    -6.712 |    0.1561 |  -0.01024 |    0.2081 |
#> |    U|     38016.187 |    -6.712 |    0.1561 |  -0.01024 |    0.2081 |
#> |   98|     38015.922 |    -6.679 |    0.1485 |  -0.01123 |    0.2085 |
#> |    U|     38015.922 |    -6.679 |    0.1485 |  -0.01123 |    0.2085 |
#> |   99|     38015.788 |    -6.531 |    0.8319 |  -0.01333 |    0.2081 |
#> |    U|     38015.788 |    -6.531 |    0.8319 |  -0.01333 |    0.2081 |
#> |  100|     38015.643 |    -6.410 |     1.109 |  -0.01427 |    0.2083 |
#> |    U|     38015.643 |    -6.410 |     1.109 |  -0.01427 |    0.2083 |
#> |  101|     38015.601 |    -6.111 |     2.250 |  -0.01786 |    0.2080 |
#> |    U|     38015.601 |    -6.111 |     2.250 |  -0.01786 |    0.2080 |
#> |  102|     38015.541 |    -6.404 |    0.8244 |  -0.01493 |    0.2093 |
#> |    U|     38015.541 |    -6.404 |    0.8244 |  -0.01493 |    0.2093 |
#> |  103|     38015.587 |    -6.249 |     1.159 |  -0.01728 |    0.2098 |
#> |    U|     38015.587 |    -6.249 |     1.159 |  -0.01728 |    0.2098 |
#> |  104|     38015.943 |    -6.069 |     1.623 |  -0.01810 |    0.2072 |
#> |    U|     38015.943 |    -6.069 |     1.623 |  -0.01810 |    0.2072 |
#> |  105|     38015.897 |    -5.800 |     3.733 |  -0.02264 |    0.2075 |
#> |    U|     38015.897 |    -5.800 |     3.733 |  -0.02264 |    0.2075 |
#> |  106|     38015.489 |    -6.354 |     2.197 |  -0.01628 |    0.2092 |
#> |    U|     38015.489 |    -6.354 |     2.197 |  -0.01628 |    0.2092 |
#> |  107|     38015.750 |    -6.497 |     2.484 |  -0.01537 |    0.2102 |
#> |    U|     38015.750 |    -6.497 |     2.484 |  -0.01537 |    0.2102 |
#> |  108|     38016.370 |    -6.900 |   -0.6808 | -0.008559 |    0.2098 |
#> |    U|     38016.370 |    -6.900 |   -0.6808 | -0.008559 |    0.2098 |
#> |  109|     38015.581 |    -6.075 |     2.629 |  -0.01912 |    0.2080 |
#> |    U|     38015.581 |    -6.075 |     2.629 |  -0.01912 |    0.2080 |
#> |  110|     38015.533 |    -5.941 |     3.118 |  -0.02076 |    0.2092 |
#> |    U|     38015.533 |    -5.941 |     3.118 |  -0.02076 |    0.2092 |
#> |  111|     38015.597 |    -6.276 |     2.134 |  -0.01769 |    0.2099 |
#> |    U|     38015.597 |    -6.276 |     2.134 |  -0.01769 |    0.2099 |
#> |  112|     38015.493 |    -6.235 |     2.163 |  -0.01773 |    0.2094 |
#> |    U|     38015.493 |    -6.235 |     2.163 |  -0.01773 |    0.2094 |
#> |  113|     38015.838 |    -6.392 |     1.522 |  -0.01573 |    0.2105 |
#> |    U|     38015.838 |    -6.392 |     1.522 |  -0.01573 |    0.2105 |
#> |  114|     38015.470 |    -6.154 |     2.352 |  -0.01827 |    0.2086 |
#> |    U|     38015.470 |    -6.154 |     2.352 |  -0.01827 |    0.2086 |
#> |  115|     38015.557 |    -5.938 |     4.091 |  -0.02159 |    0.2089 |
#> |    U|     38015.557 |    -5.938 |     4.091 |  -0.02159 |    0.2089 |
#> |  116|     38015.480 |    -6.287 |     1.641 |  -0.01660 |    0.2092 |
#> |    U|     38015.480 |    -6.287 |     1.641 |  -0.01660 |    0.2092 |
#> |  117|     38015.610 |    -6.574 |     1.058 |  -0.01368 |    0.2091 |
#> |    U|     38015.610 |    -6.574 |     1.058 |  -0.01368 |    0.2091 |
#> |  118|     38015.477 |    -6.099 |     2.603 |  -0.01899 |    0.2091 |
#> |    U|     38015.477 |    -6.099 |     2.603 |  -0.01899 |    0.2091 |
#> |  119|     38015.477 |    -6.099 |     2.603 |  -0.01899 |    0.2091 |
#> |    U|     38015.477 |    -6.099 |     2.603 |  -0.01899 |    0.2091 |
#> |  120|     38015.470 |    -6.154 |     2.352 |  -0.01827 |    0.2086 |
#> |    U|     38015.470 |    -6.154 |     2.352 |  -0.01827 |    0.2086 |
#> |  121|     38015.493 |    -6.235 |     2.163 |  -0.01773 |    0.2094 |
#> |    U|     38015.493 |    -6.235 |     2.163 |  -0.01773 |    0.2094 |
#> |  122|     38015.480 |    -6.287 |     1.641 |  -0.01660 |    0.2092 |
#> |    U|     38015.480 |    -6.287 |     1.641 |  -0.01660 |    0.2092 |
#> |  123|     38015.489 |    -6.354 |     2.197 |  -0.01628 |    0.2092 |
#> |    U|     38015.489 |    -6.354 |     2.197 |  -0.01628 |    0.2092 |
#> 
#> Error in solve.default(fit$hessian) : 
#>   Lapack routine dgesv: system is exactly singular: U[1,1] = 0

# nlmixr model example ----------------------------------------------------------
model_onecmt_bolus <- function() {
  ini({
    CL <- c(0, 5, 10) # Clearance (L/hr)
    V <- c(0, 50, 100) # Volume of Distribution
    prop.err <- c(0, 0.01, 1)
  })
  model({
    kel <- CL / V
    d / dt(X) <- -kel * X
    cp <- X / V
    cp ~ prop(prop.err)
  })
}

# note on some platforms this fit is not successful
fit <- try(nlmixr(object = model_onecmt_bolus, data = Bolus_1CPT, est = "dynmodel"))
#>  parameter labels from comments will be replaced by 'label()'
#> → creating full model...
#> → pruning branches (`if`/`else`)...
#>  done
#> → loading into symengine environment...
#>  done
#> → finding duplicate expressions in EBE model...
#> 
#> → optimizing duplicate expressions in EBE model...
#> 
#> → compiling EBE model...
#>  
#>  done
#>  
#>  
#> |-----+---------------+-----------+-----------+-----------|
#> |    #| Objective Fun |        CL |         V |      prop |
#> |    1| 4.0228158e+09 |   -0.8004 |     1.000 |    -1.000 |
#> |    U| 4.0228158e+09 |     5.000 |     50.00 |   0.01000 |
#> |    2|     10088613. |   -0.8004 |     1.000 |   -0.8100 |
#> |    U|     10088613. |     5.000 |     50.00 |    0.2000 |
#> |    3|     11311242. |   -0.6004 |     1.000 |   -0.8100 |
#> |    U|     11311242. |     5.040 |     50.00 |    0.2000 |
#> |    4|     10078717. |   -0.8004 |     1.200 |   -0.8100 |
#> |    U|     10078717. |     5.000 |     50.00 |    0.2000 |
#> |    5|     2550672.7 |   -0.8004 |     1.000 |   -0.6100 |
#> |    U|     2550672.7 |     5.000 |     50.00 |    0.4000 |
#> |    6|     8998173.4 |    -1.000 |     1.000 |   -0.8100 |
#> |    U|     8998173.4 |     4.960 |     50.00 |    0.2000 |
#> |    7|     10098520. |   -0.8004 |    0.8000 |   -0.8100 |
#> |    U|     10098520. |     5.000 |     50.00 |    0.2000 |
#> |    8| 1.8117103e+21 |   -0.8004 |     1.000 |    -1.010 |
#> |    U| 1.8117103e+21 |     5.000 |     50.00 | 1.490e-08 |
#> |    9|     4504202.9 |   -0.8004 |     1.000 |   -0.7100 |
#> |    U|     4504202.9 |     5.000 |     50.00 |    0.3000 |
#> |   10|     2114977.2 |   -0.8004 |     1.000 |   -0.5700 |
#> |    U|     2114977.2 |     5.000 |     50.00 |    0.4400 |
#> |   11|     2505577.9 |   -0.8306 |     1.000 |   -0.6098 |
#> |    U|     2505577.9 |     4.994 |     50.00 |    0.4002 |
#> |   12|     2098337.6 |   -0.7808 |    0.9993 |   -0.5657 |
#> |    U|     2098337.6 |     5.004 |     50.00 |    0.4443 |
#> |   13|     2258746.4 |   -0.7790 |     1.011 |   -0.5819 |
#> |    U|     2258746.4 |     5.004 |     50.00 |    0.4281 |
#> |   14|     1963459.6 |   -0.7796 |     1.012 |   -0.5503 |
#> |    U|     1963459.6 |     5.004 |     50.00 |    0.4597 |
#> |   15|     1826684.2 |   -0.7775 |     1.003 |   -0.5327 |
#> |    U|     1826684.2 |     5.005 |     50.00 |    0.4773 |
#> |   16|     1690689.1 |   -0.7744 |     1.002 |   -0.5130 |
#> |    U|     1690689.1 |     5.005 |     50.00 |    0.4970 |
#> |   17|     1597380.3 |   -0.7898 |     1.004 |   -0.5005 |
#> |    U|     1597380.3 |     5.002 |     50.00 |    0.5095 |
#> |   18|     1493808.6 |   -0.7881 |    0.9962 |   -0.4824 |
#> |    U|     1493808.6 |     5.002 |     50.00 |    0.5276 |
#> |   19|     1390110.2 |   -0.7924 |    0.9929 |   -0.4632 |
#> |    U|     1390110.2 |     5.002 |     50.00 |    0.5468 |
#> |   20|     1223239.5 |   -0.7872 |     1.003 |   -0.4250 |
#> |    U|     1223239.5 |     5.003 |     50.00 |    0.5850 |
#> |   21|     1075354.5 |   -0.7910 |     1.003 |   -0.3851 |
#> |    U|     1075354.5 |     5.002 |     50.00 |    0.6249 |
#> |   22|     853960.38 |   -0.7928 |    0.9979 |   -0.3053 |
#> |    U|     853960.38 |     5.002 |     50.00 |    0.7047 |
#> |   23|     731312.51 |   -0.8114 |     1.052 |   -0.2492 |
#> |    U|     731312.51 |     4.998 |     50.00 |    0.7608 |
#> |   24|     610240.75 |   -0.8030 |     1.050 |   -0.1697 |
#> |    U|     610240.75 |     4.999 |     50.00 |    0.8403 |
#> |   25|     516629.36 |   -0.8402 |     1.062 |  -0.09982 |
#> |    U|     516629.36 |     4.992 |     50.00 |    0.9102 |
#> |   26|     451805.10 |   -0.8451 |     1.103 |  -0.03132 |
#> |    U|     451805.10 |     4.991 |     50.00 |    0.9787 |
#> |   27|     435116.90 |   -0.8433 |     1.090 |  -0.01000 |
#> |    U|     435116.90 |     4.991 |     50.00 |     1.000 |
#> |   28|     431868.56 |   -0.8577 |     1.104 |  -0.01000 |
#> |    U|     431868.56 |     4.989 |     50.00 |     1.000 |
#> |   29|     432407.51 |   -0.8706 |     1.089 |  -0.01438 |
#> |    U|     432407.51 |     4.986 |     50.00 |    0.9956 |
#> |   30|     431961.54 |   -0.8575 |     1.085 |  -0.01000 |
#> |    U|     431961.54 |     4.989 |     50.00 |     1.000 |
#> |   31|     447057.83 |   -0.8542 |     1.100 |  -0.02813 |
#> |    U|     447057.83 |     4.989 |     50.00 |    0.9819 |
#> |   32|     430456.87 |   -0.8642 |     1.095 |  -0.01000 |
#> |    U|     430456.87 |     4.987 |     50.00 |     1.000 |
#> |   33|     434605.05 |   -0.8455 |     1.102 |  -0.01000 |
#> |    U|     434605.05 |     4.991 |     50.00 |     1.000 |
#> |   34|     428243.61 |   -0.8742 |     1.094 |  -0.01000 |
#> |    U|     428243.61 |     4.985 |     50.00 |     1.000 |
#> |   35|     423857.33 |   -0.8942 |     1.094 |  -0.01000 |
#> |    U|     423857.33 |     4.981 |     50.00 |     1.000 |
#> |   36|     415309.53 |   -0.9338 |     1.089 |  -0.01000 |
#> |    U|     415309.53 |     4.973 |     50.00 |     1.000 |
#> |   37|     399066.63 |    -1.012 |     1.071 |  -0.01000 |
#> |    U|     399066.63 |     4.958 |     50.00 |     1.000 |
#> |   38|     369233.42 |    -1.165 |     1.025 |  -0.01000 |
#> |    U|     369233.42 |     4.927 |     50.00 |     1.000 |
#> |   39|     315648.46 |    -1.479 |    0.9619 |  -0.01000 |
#> |    U|     315648.46 |     4.864 |     50.00 |     1.000 |
#> |   40|     232151.71 |    -2.117 |     1.007 |  -0.01000 |
#> |    U|     232151.71 |     4.737 |     50.00 |     1.000 |
#> |   41|     151420.69 |    -3.093 |    0.9638 |  -0.01000 |
#> |    U|     151420.69 |     4.542 |     50.00 |     1.000 |
#> |   42| 2.4670681e+20 |    -4.249 |     2.179 |    -1.010 |
#> |    U| 2.4670681e+20 |     4.310 |     50.02 | 1.490e-08 |
#> |   43|     221424.08 |    -3.092 |    0.9534 |   -0.2354 |
#> |    U|     221424.08 |     4.542 |     50.00 |    0.7746 |
#> |   44|     1395267.9 |    -2.411 |    0.7260 |   -0.6673 |
#> |    U|     1395267.9 |     4.678 |     49.99 |    0.3427 |
#> |   45|     153871.37 |    -3.055 |    0.7418 |  -0.01000 |
#> |    U|     153871.37 |     4.549 |     49.99 |     1.000 |
#> |   46|     139123.68 |    -3.529 |    0.7550 |  -0.07429 |
#> |    U|     139123.68 |     4.454 |     50.00 |    0.9357 |
#> |   47|     168298.62 |    -3.651 |    0.6801 |   -0.2229 |
#> |    U|     168298.62 |     4.430 |     49.99 |    0.7871 |
#> |   48|     177214.06 |    -3.305 |    0.7394 |   -0.1683 |
#> |    U|     177214.06 |     4.499 |     49.99 |    0.8417 |
#> |   49|     149635.71 |    -3.577 |    0.8490 |   -0.1360 |
#> |    U|     149635.71 |     4.445 |     50.00 |    0.8740 |
#> |   50|     139455.81 |    -3.645 |    0.7727 |   -0.1077 |
#> |    U|     139455.81 |     4.431 |     50.00 |    0.9023 |
#> |   51|     135042.78 |    -3.538 |    0.7992 |  -0.05539 |
#> |    U|     135042.78 |     4.452 |     50.00 |    0.9546 |
#> |   52|     147043.53 |    -3.502 |    0.7979 |   -0.1049 |
#> |    U|     147043.53 |     4.460 |     50.00 |    0.9051 |
#> |   53|     132893.46 |    -3.514 |    0.8002 |  -0.03655 |
#> |    U|     132893.46 |     4.457 |     50.00 |    0.9735 |
#> |   54|     135830.72 |    -3.487 |    0.7901 |  -0.04491 |
#> |    U|     135830.72 |     4.463 |     50.00 |    0.9651 |
#> |   55|     132584.19 |    -3.509 |    0.8143 |  -0.03340 |
#> |    U|     132584.19 |     4.458 |     50.00 |    0.9766 |
#> |   56|     129874.43 |    -3.514 |    0.8143 |  -0.01876 |
#> |    U|     129874.43 |     4.457 |     50.00 |    0.9912 |
#> |   57|     127035.55 |    -3.543 |    0.8156 |  -0.01000 |
#> |    U|     127035.55 |     4.452 |     50.00 |     1.000 |
#> |   58|     124183.01 |    -3.604 |    0.8160 |  -0.01000 |
#> |    U|     124183.01 |     4.439 |     50.00 |     1.000 |
#> |   59|     118817.22 |    -3.725 |    0.8009 |  -0.01000 |
#> |    U|     118817.22 |     4.415 |     50.00 |     1.000 |
#> |   60|     109102.00 |    -3.968 |    0.8214 |  -0.01000 |
#> |    U|     109102.00 |     4.366 |     50.00 |     1.000 |
#> |   61|     96470.051 |    -4.349 |    0.5162 |  -0.01000 |
#> |    U|     96470.051 |     4.290 |     49.99 |     1.000 |
#> |   62|     88124.307 |    -4.662 |   -0.4089 |  -0.01000 |
#> |    U|     88124.307 |     4.228 |     49.97 |     1.000 |
#> |   63|     76243.752 |    -5.626 |   -0.5077 |   -0.1311 |
#> |    U|     76243.752 |     4.035 |     49.97 |    0.8789 |
#> |   64|     75036.231 |    -6.330 |    -1.164 |   -0.2931 |
#> |    U|     75036.231 |     3.894 |     49.96 |    0.7169 |
#> |   65|     69546.554 |    -6.263 |    -2.133 |   -0.1911 |
#> |    U|     69546.554 |     3.908 |     49.94 |    0.8189 |
#> |   66|     69201.446 |    -6.556 |    -3.062 |   -0.2592 |
#> |    U|     69201.446 |     3.849 |     49.92 |    0.7508 |
#> |   67|     62844.914 |    -7.406 |    -3.208 |   -0.3434 |
#> |    U|     62844.914 |     3.679 |     49.92 |    0.6666 |
#> |   68|     59792.294 |    -8.520 |    -4.506 |   -0.5064 |
#> |    U|     59792.294 |     3.456 |     49.89 |    0.5036 |
#> |   69|     62097.341 |    -9.185 |    -5.850 |   -0.6319 |
#> |    U|     62097.341 |     3.323 |     49.86 |    0.3781 |
#> |   70|     50389.852 |    -8.875 |    -4.906 |  -0.01000 |
#> |    U|     50389.852 |     3.385 |     49.88 |     1.000 |
#> |   71|     49887.545 |    -9.349 |    -6.318 |   -0.2269 |
#> |    U|     49887.545 |     3.290 |     49.85 |    0.7831 |
#> |   72|     49009.140 |    -10.03 |    -6.022 |  -0.09961 |
#> |    U|     49009.140 |     3.154 |     49.86 |    0.9104 |
#> |   73|     48417.783 |    -10.61 |    -5.723 |   -0.4647 |
#> |    U|     48417.783 |     3.037 |     49.87 |    0.5453 |
#> |   74|     48228.238 |    -10.89 |    -5.789 |   -0.2160 |
#> |    U|     48228.238 |     2.982 |     49.86 |    0.7940 |
#> |   75|     48211.807 |    -10.56 |    -5.946 |   -0.3063 |
#> |    U|     48211.807 |     3.048 |     49.86 |    0.7037 |
#> |   76|     48085.010 |    -10.71 |    -6.056 |   -0.3081 |
#> |    U|     48085.010 |     3.018 |     49.86 |    0.7019 |
#> |   77|     48133.830 |    -10.62 |    -6.214 |   -0.3469 |
#> |    U|     48133.830 |     3.036 |     49.86 |    0.6631 |
#> |   78|     48301.035 |    -10.67 |    -6.050 |   -0.2223 |
#> |    U|     48301.035 |     3.025 |     49.86 |    0.7877 |
#> |   79|     48014.316 |    -10.75 |    -6.037 |   -0.3936 |
#> |    U|     48014.316 |     3.011 |     49.86 |    0.6164 |
#> |   80|     48012.315 |    -10.81 |    -5.990 |   -0.4387 |
#> |    U|     48012.315 |     2.997 |     49.86 |    0.5713 |
#> |   81|     48045.083 |    -10.79 |    -5.964 |   -0.4413 |
#> |    U|     48045.083 |     3.001 |     49.86 |    0.5687 |
#> |   82|     47995.457 |    -10.83 |    -6.033 |   -0.4412 |
#> |    U|     47995.457 |     2.993 |     49.86 |    0.5688 |
#> |   83|     48051.468 |    -10.83 |    -6.077 |   -0.4568 |
#> |    U|     48051.468 |     2.994 |     49.86 |    0.5532 |
#> |   84|     47939.829 |    -10.84 |    -6.035 |   -0.4194 |
#> |    U|     47939.829 |     2.992 |     49.86 |    0.5906 |
#> |   85|     47906.512 |    -10.85 |    -6.032 |   -0.3995 |
#> |    U|     47906.512 |     2.989 |     49.86 |    0.6105 |
#> |   86|     47878.800 |    -10.89 |    -6.016 |   -0.3697 |
#> |    U|     47878.800 |     2.983 |     49.86 |    0.6403 |
#> |   87|     47836.602 |    -10.93 |    -6.009 |   -0.3930 |
#> |    U|     47836.602 |     2.975 |     49.86 |    0.6170 |
#> |   88|     47804.957 |    -11.00 |    -5.986 |   -0.4435 |
#> |    U|     47804.957 |     2.960 |     49.86 |    0.5665 |
#> |   89|     47711.718 |    -11.09 |    -5.944 |   -0.4352 |
#> |    U|     47711.718 |     2.943 |     49.86 |    0.5748 |
#> |   90|     47587.464 |    -11.25 |    -5.847 |   -0.4504 |
#> |    U|     47587.464 |     2.911 |     49.86 |    0.5596 |
#> |   91|     47615.885 |    -11.57 |    -5.677 |   -0.5491 |
#> |    U|     47615.885 |     2.847 |     49.87 |    0.4609 |
#> |   92|     47555.303 |    -11.28 |    -5.908 |   -0.4392 |
#> |    U|     47555.303 |     2.904 |     49.86 |    0.5708 |
#> |   93|     47466.399 |    -11.46 |    -5.840 |   -0.4171 |
#> |    U|     47466.399 |     2.869 |     49.86 |    0.5929 |
#> |   94|     47300.175 |    -11.74 |    -5.791 |   -0.4644 |
#> |    U|     47300.175 |     2.812 |     49.86 |    0.5456 |
#> |   95|     47425.531 |    -12.27 |    -6.028 |   -0.5908 |
#> |    U|     47425.531 |     2.707 |     49.86 |    0.4192 |
#> |   96|     47452.614 |    -11.71 |    -5.746 |   -0.3862 |
#> |    U|     47452.614 |     2.818 |     49.87 |    0.6238 |
#> |   97|     47204.926 |    -12.03 |    -5.797 |   -0.5048 |
#> |    U|     47204.926 |     2.753 |     49.86 |    0.5052 |
#> |   98|     47204.702 |    -12.17 |    -5.801 |   -0.5329 |
#> |    U|     47204.702 |     2.727 |     49.86 |    0.4771 |
#> |   99|     47355.331 |    -12.19 |    -5.806 |   -0.4093 |
#> |    U|     47355.331 |     2.721 |     49.86 |    0.6007 |
#> |  100|     47202.272 |    -12.08 |    -5.819 |   -0.5174 |
#> |    U|     47202.272 |     2.743 |     49.86 |    0.4926 |
#> |  101|     47193.129 |    -12.11 |    -5.787 |   -0.5160 |
#> |    U|     47193.129 |     2.737 |     49.86 |    0.4940 |
#> |  102|     47189.038 |    -12.10 |    -5.727 |   -0.5057 |
#> |    U|     47189.038 |     2.740 |     49.87 |    0.5043 |
#> |  103|     47192.044 |    -12.09 |    -5.744 |   -0.5080 |
#> |    U|     47192.044 |     2.742 |     49.87 |    0.5020 |
#> |  104|     47200.871 |    -12.09 |    -5.717 |   -0.5178 |
#> |    U|     47200.871 |     2.742 |     49.87 |    0.4922 |
#> |  105|     47186.180 |    -12.12 |    -5.723 |   -0.4932 |
#> |    U|     47186.180 |     2.737 |     49.87 |    0.5168 |
#> |  106|     47182.260 |    -12.13 |    -5.715 |   -0.4977 |
#> |    U|     47182.260 |     2.734 |     49.87 |    0.5123 |
#> |  107|     47176.637 |    -12.17 |    -5.697 |   -0.5042 |
#> |    U|     47176.637 |     2.727 |     49.87 |    0.5058 |
#> |  108|     47170.435 |    -12.22 |    -5.683 |   -0.5093 |
#> |    U|     47170.435 |     2.717 |     49.87 |    0.5007 |
#> |  109|     47168.394 |    -12.24 |    -5.674 |   -0.5118 |
#> |    U|     47168.394 |     2.713 |     49.87 |    0.4982 |
#> |  110|     47164.677 |    -12.27 |    -5.632 |   -0.5101 |
#> |    U|     47164.677 |     2.707 |     49.87 |    0.4999 |
#> |  111|     47161.380 |    -12.31 |    -5.609 |   -0.5102 |
#> |    U|     47161.380 |     2.698 |     49.87 |    0.4998 |
#> |  112|     47159.144 |    -12.40 |    -5.587 |   -0.5183 |
#> |    U|     47159.144 |     2.680 |     49.87 |    0.4917 |
#> |  113|     47158.726 |    -12.39 |    -5.581 |   -0.5157 |
#> |    U|     47158.726 |     2.682 |     49.87 |    0.4943 |
#> |  114|     47158.556 |    -12.40 |    -5.575 |   -0.5152 |
#> |    U|     47158.556 |     2.681 |     49.87 |    0.4948 |
#> |  115|     47158.404 |    -12.41 |    -5.561 |   -0.5147 |
#> |    U|     47158.404 |     2.677 |     49.87 |    0.4953 |
#> |  116|     47158.437 |    -12.42 |    -5.560 |   -0.5152 |
#> |    U|     47158.437 |     2.677 |     49.87 |    0.4948 |
#> |  117|     47158.597 |    -12.41 |    -5.560 |   -0.5166 |
#> |    U|     47158.597 |     2.677 |     49.87 |    0.4934 |
#> |  118|     47158.419 |    -12.41 |    -5.561 |   -0.5128 |
#> |    U|     47158.419 |     2.677 |     49.87 |    0.4972 |
#> |  119|     47158.378 |    -12.41 |    -5.559 |   -0.5142 |
#> |    U|     47158.378 |     2.677 |     49.87 |    0.4958 |
#> |  120|     47158.373 |    -12.41 |    -5.559 |   -0.5134 |
#> |    U|     47158.373 |     2.678 |     49.87 |    0.4966 |
#> |  121|     47158.378 |    -12.41 |    -5.558 |   -0.5135 |
#> |    U|     47158.378 |     2.677 |     49.87 |    0.4965 |
#> |  122|     47158.485 |    -12.41 |    -5.560 |   -0.5117 |
#> |    U|     47158.485 |     2.678 |     49.87 |    0.4983 |
#> |  123|     47158.373 |    -12.41 |    -5.561 |   -0.5138 |
#> |    U|     47158.373 |     2.678 |     49.87 |    0.4962 |
#> |  124|     47158.391 |    -12.41 |    -5.563 |   -0.5145 |
#> |    U|     47158.391 |     2.678 |     49.87 |    0.4955 |
#> |  125|     47158.373 |    -12.41 |    -5.559 |   -0.5137 |
#> |    U|     47158.373 |     2.677 |     49.87 |    0.4963 |
#> |  126|     47158.365 |    -12.41 |    -5.557 |   -0.5136 |
#> |    U|     47158.365 |     2.678 |     49.87 |    0.4964 |
#> |  127|     47158.362 |    -12.41 |    -5.555 |   -0.5134 |
#> |    U|     47158.362 |     2.678 |     49.87 |    0.4966 |
#> |  128|     47158.354 |    -12.41 |    -5.554 |   -0.5133 |
#> |    U|     47158.354 |     2.678 |     49.87 |    0.4967 |
#> |  129|     47158.338 |    -12.41 |    -5.551 |   -0.5132 |
#> |    U|     47158.338 |     2.678 |     49.87 |    0.4968 |
#> |  130|     47158.332 |    -12.40 |    -5.544 |   -0.5125 |
#> |    U|     47158.332 |     2.679 |     49.87 |    0.4975 |
#> |  131|     47158.336 |    -12.40 |    -5.545 |   -0.5125 |
#> |    U|     47158.336 |     2.679 |     49.87 |    0.4975 |
#> |  132|     47158.330 |    -12.40 |    -5.545 |   -0.5127 |
#> |    U|     47158.330 |     2.679 |     49.87 |    0.4973 |
#> |  133|     47158.308 |    -12.40 |    -5.544 |   -0.5132 |
#> |    U|     47158.308 |     2.679 |     49.87 |    0.4968 |
#> |  134|     47158.302 |    -12.40 |    -5.540 |   -0.5133 |
#> |    U|     47158.302 |     2.680 |     49.87 |    0.4967 |
#> |  135|     47158.293 |    -12.40 |    -5.537 |   -0.5132 |
#> |    U|     47158.293 |     2.680 |     49.87 |    0.4968 |
#> |  136|     47158.293 |    -12.40 |    -5.530 |   -0.5131 |
#> |    U|     47158.293 |     2.681 |     49.87 |    0.4969 |
#> |  137|     47158.559 |    -12.40 |    -5.529 |   -0.5100 |
#> |    U|     47158.559 |     2.681 |     49.87 |    0.5000 |
#> |  138|     47158.279 |    -12.40 |    -5.526 |   -0.5130 |
#> |    U|     47158.279 |     2.681 |     49.87 |    0.4970 |
#> |  139|     47158.272 |    -12.39 |    -5.518 |   -0.5129 |
#> |    U|     47158.272 |     2.681 |     49.87 |    0.4971 |
#> |  140|     47158.285 |    -12.39 |    -5.503 |   -0.5125 |
#> |    U|     47158.285 |     2.683 |     49.87 |    0.4975 |
#> |  141|     47158.491 |    -12.39 |    -5.519 |   -0.5155 |
#> |    U|     47158.491 |     2.682 |     49.87 |    0.4945 |
#> |  142|     47158.264 |    -12.39 |    -5.515 |   -0.5130 |
#> |    U|     47158.264 |     2.681 |     49.87 |    0.4970 |
#> |  143|     47158.244 |    -12.39 |    -5.510 |   -0.5130 |
#> |    U|     47158.244 |     2.681 |     49.87 |    0.4970 |
#> |  144|     47158.223 |    -12.39 |    -5.499 |   -0.5131 |
#> |    U|     47158.223 |     2.682 |     49.87 |    0.4969 |
#> |  145|     47158.227 |    -12.39 |    -5.488 |   -0.5131 |
#> |    U|     47158.227 |     2.682 |     49.87 |    0.4969 |
#> |  146|     47158.519 |    -12.39 |    -5.499 |   -0.5162 |
#> |    U|     47158.519 |     2.682 |     49.87 |    0.4938 |
#> |  147|     47158.207 |    -12.39 |    -5.493 |   -0.5130 |
#> |    U|     47158.207 |     2.682 |     49.87 |    0.4970 |
#> |  148|     47158.160 |    -12.39 |    -5.482 |   -0.5133 |
#> |    U|     47158.160 |     2.681 |     49.87 |    0.4967 |
#> |  149|     47158.081 |    -12.40 |    -5.459 |   -0.5138 |
#> |    U|     47158.081 |     2.681 |     49.87 |    0.4962 |
#> |  150|     47157.950 |    -12.40 |    -5.414 |   -0.5137 |
#> |    U|     47157.950 |     2.681 |     49.87 |    0.4963 |
#> |  151|     47157.790 |    -12.41 |    -5.370 |   -0.5141 |
#> |    U|     47157.790 |     2.679 |     49.87 |    0.4959 |
#> |  152|     47157.647 |    -12.41 |    -5.325 |   -0.5137 |
#> |    U|     47157.647 |     2.679 |     49.87 |    0.4963 |
#> |  153|     47157.563 |    -12.41 |    -5.234 |   -0.5163 |
#> |    U|     47157.563 |     2.678 |     49.88 |    0.4937 |
#> |  154|     47157.196 |    -12.42 |    -5.144 |   -0.5146 |
#> |    U|     47157.196 |     2.676 |     49.88 |    0.4954 |
#> |  155|     47156.919 |    -12.44 |    -4.963 |   -0.5152 |
#> |    U|     47156.919 |     2.673 |     49.88 |    0.4948 |
#> |  156|     47156.560 |    -12.45 |    -4.702 |   -0.5159 |
#> |    U|     47156.560 |     2.669 |     49.89 |    0.4941 |
#> |  157|     47156.053 |    -12.46 |    -4.380 |   -0.5172 |
#> |    U|     47156.053 |     2.667 |     49.89 |    0.4928 |
#> |  158|     47155.531 |    -12.47 |    -4.087 |   -0.5179 |
#> |    U|     47155.531 |     2.666 |     49.90 |    0.4921 |
#> |  159|     47155.881 |    -12.47 |    -3.499 |   -0.5082 |
#> |    U|     47155.881 |     2.665 |     49.91 |    0.5018 |
#> |  160|     47513.855 |    -12.45 |    -4.086 |   -0.3777 |
#> |    U|     47513.855 |     2.670 |     49.90 |    0.6323 |
#> |  161|     47172.230 |    -12.34 |    -4.350 |   -0.4859 |
#> |    U|     47172.230 |     2.691 |     49.89 |    0.5241 |
#> |  162|     47196.008 |    -12.33 |    -4.082 |   -0.5467 |
#> |    U|     47196.008 |     2.693 |     49.90 |    0.4633 |
#> |  163|     47181.906 |    -12.50 |    -4.227 |   -0.4870 |
#> |    U|     47181.906 |     2.659 |     49.90 |    0.5230 |
#> |  164|     47167.507 |    -12.50 |    -4.039 |   -0.4976 |
#> |    U|     47167.507 |     2.660 |     49.90 |    0.5124 |
#> |  165|     47157.636 |    -12.41 |    -4.048 |   -0.5023 |
#> |    U|     47157.636 |     2.678 |     49.90 |    0.5077 |
#> |  166|     47155.094 |    -12.46 |    -4.113 |   -0.5147 |
#> |    U|     47155.094 |     2.668 |     49.90 |    0.4953 |
#> |  167|     47156.296 |    -12.46 |    -4.090 |   -0.5091 |
#> |    U|     47156.296 |     2.668 |     49.90 |    0.5009 |
#> |  168|     47156.331 |    -12.47 |    -4.116 |   -0.5113 |
#> |    U|     47156.331 |     2.666 |     49.90 |    0.4987 |
#> |  169|     47154.906 |    -12.45 |    -4.098 |   -0.5178 |
#> |    U|     47154.906 |     2.670 |     49.90 |    0.4922 |
#> |  170|     47154.937 |    -12.45 |    -4.102 |   -0.5173 |
#> |    U|     47154.937 |     2.669 |     49.90 |    0.4927 |
#> |  171|     47154.994 |    -12.45 |    -4.094 |   -0.5187 |
#> |    U|     47154.994 |     2.670 |     49.90 |    0.4913 |
#> |  172|     47154.774 |    -12.45 |    -4.101 |   -0.5171 |
#> |    U|     47154.774 |     2.670 |     49.90 |    0.4929 |
#> |  173|     47154.542 |    -12.44 |    -4.104 |   -0.5162 |
#> |    U|     47154.542 |     2.672 |     49.90 |    0.4938 |
#> |  174|     47154.293 |    -12.43 |    -4.113 |   -0.5157 |
#> |    U|     47154.293 |     2.674 |     49.90 |    0.4943 |
#> |  175|     47154.217 |    -12.42 |    -4.123 |   -0.5161 |
#> |    U|     47154.217 |     2.676 |     49.90 |    0.4939 |
#> |  176|     47154.225 |    -12.42 |    -4.123 |   -0.5162 |
#> |    U|     47154.225 |     2.676 |     49.90 |    0.4938 |
#> |  177|     47154.307 |    -12.42 |    -4.123 |   -0.5169 |
#> |    U|     47154.307 |     2.676 |     49.90 |    0.4931 |
#> |  178|     47154.159 |    -12.42 |    -4.123 |   -0.5154 |
#> |    U|     47154.159 |     2.676 |     49.90 |    0.4946 |
#> |  179|     47154.143 |    -12.42 |    -4.124 |   -0.5143 |
#> |    U|     47154.143 |     2.676 |     49.90 |    0.4957 |
#> |  180|     47154.125 |    -12.42 |    -4.124 |   -0.5141 |
#> |    U|     47154.125 |     2.676 |     49.90 |    0.4959 |
#> |  181|     47154.096 |    -12.42 |    -4.125 |   -0.5142 |
#> |    U|     47154.096 |     2.677 |     49.90 |    0.4958 |
#> |  182|     47154.066 |    -12.41 |    -4.129 |   -0.5138 |
#> |    U|     47154.066 |     2.678 |     49.90 |    0.4962 |
#> |  183|     47154.056 |    -12.40 |    -4.133 |   -0.5135 |
#> |    U|     47154.056 |     2.679 |     49.90 |    0.4965 |
#> |  184|     47154.056 |    -12.40 |    -4.133 |   -0.5136 |
#> |    U|     47154.056 |     2.679 |     49.90 |    0.4964 |
#> |  185|     47154.052 |    -12.40 |    -4.132 |   -0.5138 |
#> |    U|     47154.052 |     2.679 |     49.90 |    0.4962 |
#> |  186|     47154.056 |    -12.40 |    -4.133 |   -0.5141 |
#> |    U|     47154.056 |     2.679 |     49.90 |    0.4959 |
#> |  187|     47154.055 |    -12.40 |    -4.132 |   -0.5135 |
#> |    U|     47154.055 |     2.679 |     49.90 |    0.4965 |
#> |  188|     47154.051 |    -12.40 |    -4.132 |   -0.5138 |
#> |    U|     47154.051 |     2.679 |     49.90 |    0.4962 |
#> |  189|     47154.050 |    -12.40 |    -4.132 |   -0.5139 |
#> |    U|     47154.050 |     2.680 |     49.90 |    0.4961 |
#> |  190|     47154.051 |    -12.40 |    -4.132 |   -0.5140 |
#> |    U|     47154.051 |     2.680 |     49.90 |    0.4960 |
#> |  191|     47154.054 |    -12.40 |    -4.132 |   -0.5134 |
#> |    U|     47154.054 |     2.680 |     49.90 |    0.4966 |
#> |  192|     47154.047 |    -12.40 |    -4.131 |   -0.5139 |
#> |    U|     47154.047 |     2.680 |     49.90 |    0.4961 |
#> |  193|     47154.043 |    -12.40 |    -4.130 |   -0.5139 |
#> |    U|     47154.043 |     2.680 |     49.90 |    0.4961 |
#> |  194|     47154.044 |    -12.40 |    -4.128 |   -0.5142 |
#> |    U|     47154.044 |     2.680 |     49.90 |    0.4958 |
#> |  195|     47154.043 |    -12.40 |    -4.130 |   -0.5140 |
#> |    U|     47154.043 |     2.680 |     49.90 |    0.4960 |
#> |  196|     47154.043 |    -12.40 |    -4.129 |   -0.5140 |
#> |    U|     47154.043 |     2.679 |     49.90 |    0.4960 |
#> |  197|     47154.051 |    -12.40 |    -4.129 |   -0.5143 |
#> |    U|     47154.051 |     2.679 |     49.90 |    0.4957 |
#> |  198|     47154.041 |    -12.40 |    -4.129 |   -0.5138 |
#> |    U|     47154.041 |     2.679 |     49.90 |    0.4962 |
#> |  199|     47154.038 |    -12.40 |    -4.128 |   -0.5137 |
#> |    U|     47154.038 |     2.680 |     49.90 |    0.4963 |
#> |  200|     47154.034 |    -12.40 |    -4.127 |   -0.5137 |
#> |    U|     47154.034 |     2.680 |     49.90 |    0.4963 |
#> |  201|     47154.029 |    -12.40 |    -4.125 |   -0.5134 |
#> |    U|     47154.029 |     2.680 |     49.90 |    0.4966 |
#> |  202|     47154.024 |    -12.40 |    -4.122 |   -0.5134 |
#> |    U|     47154.024 |     2.681 |     49.90 |    0.4966 |
#> |  203|     47154.024 |    -12.40 |    -4.122 |   -0.5134 |
#> |    U|     47154.024 |     2.681 |     49.90 |    0.4966 |
#> |  204|     47154.024 |    -12.40 |    -4.122 |   -0.5134 |
#> |    U|     47154.024 |     2.681 |     49.90 |    0.4966 |
#> |  205|     47154.024 |    -12.40 |    -4.122 |   -0.5136 |
#> |    U|     47154.024 |     2.681 |     49.90 |    0.4964 |
#> |  206|     47154.023 |    -12.40 |    -4.122 |   -0.5135 |
#> |    U|     47154.023 |     2.681 |     49.90 |    0.4965 |
#> |  207|     47154.022 |    -12.40 |    -4.122 |   -0.5135 |
#> |    U|     47154.022 |     2.681 |     49.90 |    0.4965 |
#> |  208|     47154.020 |    -12.40 |    -4.122 |   -0.5135 |
#> |    U|     47154.020 |     2.681 |     49.90 |    0.4965 |
#> |  209|     47154.016 |    -12.40 |    -4.121 |   -0.5135 |
#> |    U|     47154.016 |     2.681 |     49.90 |    0.4965 |
#> |  210|     47154.008 |    -12.40 |    -4.118 |   -0.5136 |
#> |    U|     47154.008 |     2.681 |     49.90 |    0.4964 |
#> |  211|     47153.994 |    -12.40 |    -4.114 |   -0.5136 |
#> |    U|     47153.994 |     2.680 |     49.90 |    0.4964 |
#> |  212|     47153.971 |    -12.40 |    -4.105 |   -0.5137 |
#> |    U|     47153.971 |     2.681 |     49.90 |    0.4963 |
#> |  213|     47153.946 |    -12.40 |    -4.098 |   -0.5139 |
#> |    U|     47153.946 |     2.680 |     49.90 |    0.4961 |
#> |  214|     47153.894 |    -12.40 |    -4.080 |   -0.5140 |
#> |    U|     47153.894 |     2.680 |     49.90 |    0.4960 |
#> |  215|     47153.813 |    -12.40 |    -4.044 |   -0.5148 |
#> |    U|     47153.813 |     2.679 |     49.90 |    0.4952 |
#> |  216|     47153.580 |    -12.39 |    -3.972 |   -0.5135 |
#> |    U|     47153.580 |     2.681 |     49.90 |    0.4965 |
#> |  217|     47153.141 |    -12.40 |    -3.827 |   -0.5141 |
#> |    U|     47153.141 |     2.681 |     49.90 |    0.4959 |
#> |  218|     47152.353 |    -12.42 |    -3.538 |   -0.5140 |
#> |    U|     47152.353 |     2.677 |     49.91 |    0.4960 |
#> |  219|     47150.577 |    -12.38 |    -2.960 |   -0.5138 |
#> |    U|     47150.577 |     2.683 |     49.92 |    0.4962 |
#> |  220|     47147.260 |    -12.40 |    -1.802 |   -0.5169 |
#> |    U|     47147.260 |     2.681 |     49.94 |    0.4931 |
#> |  221|     47140.437 |    -12.36 |    0.5153 |   -0.5163 |
#> |    U|     47140.437 |     2.687 |     49.99 |    0.4937 |
#> |  222|     47126.652 |    -12.35 |     5.149 |   -0.5176 |
#> |    U|     47126.652 |     2.690 |     50.08 |    0.4924 |
#> |  223|     47098.527 |    -12.35 |     14.42 |   -0.5160 |
#> |    U|     47098.527 |     2.690 |     50.27 |    0.4940 |
#> |  224|     47043.745 |    -12.28 |     32.95 |   -0.5196 |
#> |    U|     47043.745 |     2.703 |     50.64 |    0.4904 |
#> |  225|     46950.846 |    -12.34 |     70.03 |   -0.5389 |
#> |    U|     46950.846 |     2.692 |     51.38 |    0.4711 |
#> |  226|     46736.538 |    -11.79 |     144.2 |   -0.5101 |
#> |    U|     46736.538 |     2.801 |     52.86 |    0.4999 |
#> |  227|     46379.912 |    -11.11 |     292.5 |   -0.5382 |
#> |    U|     46379.912 |     2.938 |     55.83 |    0.4718 |
#> |  228|     45780.390 |    -10.02 |     589.0 |   -0.5458 |
#> |    U|     45780.390 |     3.156 |     61.76 |    0.4642 |
#> |  229|     45170.448 |    -7.998 |     1182. |   -0.5683 |
#> |    U|     45170.448 |     3.561 |     73.62 |    0.4417 |
#> |  230|     45182.399 |    -7.480 |     1339. |   -0.5809 |
#> |    U|     45182.399 |     3.664 |     76.75 |    0.4291 |
#> |  231| 1.1628688e+24 |     24.20 |     1068. |    -1.010 |
#> |    U| 1.1628688e+24 |     10.00 |     71.34 | 1.490e-08 |
#> |  232|     71358.017 |    -25.80 |     1338. |  -0.01000 |
#> |    U|     71358.017 | 1.490e-08 |     76.73 |     1.000 |
#> |  233| 1.0482126e+19 |    -25.80 |     1258. |    -1.010 |
#> |    U| 1.0482126e+19 | 1.490e-08 |     75.15 | 1.490e-08 |
#> |  234|     51648.684 |    -16.47 |     1260. |  -0.01000 |
#> |    U|     51648.684 |     1.865 |     75.18 |     1.000 |
#> |  235|     71726.733 |    -25.80 |     1147. |  -0.01000 |
#> |    U|     71726.733 | 1.490e-08 |     72.93 |     1.000 |
#> |  236| 4.2455839e+18 |    -16.00 |     1144. |    -1.010 |
#> |    U| 4.2455839e+18 |     1.961 |     72.86 | 1.490e-08 |
#> |  237| 9.2926641e+20 |     7.276 |     1186. |    -1.010 |
#> |    U| 9.2926641e+20 |     6.615 |     73.69 | 1.490e-08 |
#> |  238| 1.1320892e+19 |    -4.112 |     1201. |    -1.010 |
#> |    U| 1.1320892e+19 |     4.338 |     74.01 | 1.490e-08 |
#> |  239| 4.1720570e+18 |    -15.80 |     1183. |    -1.010 |
#> |    U| 4.1720570e+18 |     2.000 |     73.63 | 1.490e-08 |
#> |  240| 2.5526835e+19 |    -2.061 |     1174. |    -1.010 |
#> |    U| 2.5526835e+19 |     4.748 |     73.47 | 1.490e-08 |
#> |  241|     49160.317 |    -12.24 |     1185. |  -0.01000 |
#> |    U|     49160.317 |     2.712 |     73.67 |     1.000 |
#> |  242|     47225.265 |    -6.753 |     1178. |  -0.01000 |
#> |    U|     47225.265 |     3.809 |     73.53 |     1.000 |
#> |  243| 3.3300653e+18 |    -8.674 |     1184. |    -1.010 |
#> |    U| 3.3300653e+18 |     3.425 |     73.66 | 1.490e-08 |
#> |  244| 3.0408222e+18 |    -9.577 |     1180. |    -1.010 |
#> |    U| 3.0408222e+18 |     3.245 |     73.59 | 1.490e-08 |
#> |  245|     47253.539 |    -7.020 |     1183. |  -0.01000 |
#> |    U|     47253.539 |     3.756 |     73.63 |     1.000 |
#> |  246|     47665.274 |    -8.746 |     1183. |  -0.01000 |
#> |    U|     47665.274 |     3.411 |     73.64 |     1.000 |
#> |  247|     45864.031 |    -7.573 |     1182. |   -0.6241 |
#> |    U|     45864.031 |     3.645 |     73.62 |    0.3859 |
#> |  248|     47392.757 |    -7.766 |     1182. |  -0.01000 |
#> |    U|     47392.757 |     3.607 |     73.62 |     1.000 |
#> |  249|     45348.271 |    -8.156 |     1182. |   -0.6125 |
#> |    U|     45348.271 |     3.529 |     73.62 |    0.3975 |
#> |  250|     51679.124 |    -7.981 |     1182. |   -0.7765 |
#> |    U|     51679.124 |     3.564 |     73.62 |    0.2335 |
#> |  251|     45590.690 |    -7.972 |     1182. |   -0.6271 |
#> |    U|     45590.690 |     3.566 |     73.63 |    0.3829 |
#> |  252|     45151.140 |    -7.917 |     1182. |   -0.4840 |
#> |    U|     45151.140 |     3.577 |     73.63 |    0.5260 |
#> |  253|     45215.526 |    -7.971 |     1182. |   -0.4533 |
#> |    U|     45215.526 |     3.566 |     73.63 |    0.5567 |
#> |  254|     45257.518 |    -7.856 |     1182. |   -0.4430 |
#> |    U|     45257.518 |     3.589 |     73.63 |    0.5670 |
#> |  255|     45207.012 |    -7.926 |     1182. |   -0.4581 |
#> |    U|     45207.012 |     3.575 |     73.63 |    0.5519 |
#> |  256|     45126.255 |    -7.894 |     1182. |   -0.5129 |
#> |    U|     45126.255 |     3.581 |     73.63 |    0.4971 |
#> |  257|     45138.882 |    -7.844 |     1182. |   -0.5142 |
#> |    U|     45138.882 |     3.591 |     73.63 |    0.4958 |
#> |  258|     45133.223 |    -7.868 |     1182. |   -0.5219 |
#> |    U|     45133.223 |     3.587 |     73.63 |    0.4881 |
#> |  259|     45120.848 |    -7.913 |     1182. |   -0.5158 |
#> |    U|     45120.848 |     3.578 |     73.63 |    0.4942 |
#> |  260|     45116.984 |    -7.928 |     1182. |   -0.5234 |
#> |    U|     45116.984 |     3.574 |     73.62 |    0.4866 |
#> |  261|     45110.147 |    -7.956 |     1182. |   -0.5256 |
#> |    U|     45110.147 |     3.569 |     73.62 |    0.4844 |
#> |  262|     45106.699 |    -7.981 |     1182. |   -0.5325 |
#> |    U|     45106.699 |     3.564 |     73.62 |    0.4775 |
#> |  263|     45103.627 |    -8.006 |     1182. |   -0.5374 |
#> |    U|     45103.627 |     3.559 |     73.62 |    0.4726 |
#> |  264|     45105.694 |    -8.047 |     1182. |   -0.5484 |
#> |    U|     45105.694 |     3.551 |     73.62 |    0.4616 |
#> |  265|     45128.954 |    -7.988 |     1182. |   -0.5514 |
#> |    U|     45128.954 |     3.562 |     73.62 |    0.4586 |
#> |  266|     45089.736 |    -8.041 |     1182. |   -0.5220 |
#> |    U|     45089.736 |     3.552 |     73.62 |    0.4880 |
#> |  267|     45077.540 |    -8.097 |     1182. |   -0.5254 |
#> |    U|     45077.540 |     3.541 |     73.62 |    0.4846 |
#> |  268|     45059.127 |    -8.199 |     1182. |   -0.5389 |
#> |    U|     45059.127 |     3.520 |     73.62 |    0.4711 |
#> |  269|     45041.308 |    -8.303 |     1182. |   -0.5423 |
#> |    U|     45041.308 |     3.499 |     73.62 |    0.4677 |
#> |  270|     45030.235 |    -8.511 |     1182. |   -0.5650 |
#> |    U|     45030.235 |     3.458 |     73.61 |    0.4450 |
#> |  271|     45014.538 |    -8.559 |     1182. |   -0.5571 |
#> |    U|     45014.538 |     3.448 |     73.61 |    0.4529 |
#> |  272|     45004.063 |    -8.678 |     1182. |   -0.5395 |
#> |    U|     45004.063 |     3.425 |     73.61 |    0.4705 |
#> |  273|     45004.602 |    -8.707 |     1181. |   -0.5376 |
#> |    U|     45004.602 |     3.419 |     73.61 |    0.4724 |
#> |  274|     45180.782 |    -8.691 |     1182. |   -0.6144 |
#> |    U|     45180.782 |     3.422 |     73.61 |    0.3956 |
#> |  275|     45000.682 |    -8.694 |     1181. |   -0.5505 |
#> |    U|     45000.682 |     3.421 |     73.61 |    0.4595 |
#> |  276|     45007.830 |    -8.715 |     1181. |   -0.5651 |
#> |    U|     45007.830 |     3.417 |     73.61 |    0.4449 |
#> |  277|     45002.070 |    -8.730 |     1181. |   -0.5406 |
#> |    U|     45002.070 |     3.414 |     73.61 |    0.4694 |
#> |  278|     45002.613 |    -8.719 |     1181. |   -0.5401 |
#> |    U|     45002.613 |     3.416 |     73.61 |    0.4699 |
#> |  279|     45013.488 |    -8.686 |     1181. |   -0.5678 |
#> |    U|     45013.488 |     3.423 |     73.61 |    0.4422 |
#> |  280|     45001.962 |    -8.699 |     1181. |   -0.5423 |
#> |    U|     45001.962 |     3.420 |     73.61 |    0.4677 |
#> |  281|     45002.395 |    -8.693 |     1181. |   -0.5564 |
#> |    U|     45002.395 |     3.421 |     73.61 |    0.4536 |
#> |  282|     45000.300 |    -8.703 |     1181. |   -0.5514 |
#> |    U|     45000.300 |     3.419 |     73.61 |    0.4586 |
#> |  283|     44999.791 |    -8.712 |     1181. |   -0.5502 |
#> |    U|     44999.791 |     3.418 |     73.61 |    0.4598 |
#> |  284|     44999.074 |    -8.730 |     1181. |   -0.5510 |
#> |    U|     44999.074 |     3.414 |     73.61 |    0.4590 |
#> |  285|     44998.394 |    -8.749 |     1181. |   -0.5511 |
#> |    U|     44998.394 |     3.410 |     73.61 |    0.4589 |
#> |  286|     44997.361 |    -8.787 |     1181. |   -0.5528 |
#> |    U|     44997.361 |     3.403 |     73.61 |    0.4572 |
#> |  287|     44996.637 |    -8.862 |     1181. |   -0.5568 |
#> |    U|     44996.637 |     3.388 |     73.61 |    0.4532 |
#> |  288|     44996.653 |    -8.860 |     1181. |   -0.5567 |
#> |    U|     44996.653 |     3.388 |     73.61 |    0.4533 |
#> |  289|     44996.743 |    -8.862 |     1181. |   -0.5509 |
#> |    U|     44996.743 |     3.388 |     73.61 |    0.4591 |
#> |  290|     44996.412 |    -8.858 |     1181. |   -0.5541 |
#> |    U|     44996.412 |     3.389 |     73.61 |    0.4559 |
#> |  291|     44996.470 |    -8.846 |     1181. |   -0.5535 |
#> |    U|     44996.470 |     3.391 |     73.61 |    0.4565 |
#> |  292|     44996.490 |    -8.862 |     1181. |   -0.5557 |
#> |    U|     44996.490 |     3.388 |     73.61 |    0.4543 |
#> |  293|     44996.425 |    -8.857 |     1181. |   -0.5533 |
#> |    U|     44996.425 |     3.389 |     73.61 |    0.4567 |
#> |  294|     44996.418 |    -8.856 |     1181. |   -0.5542 |
#> |    U|     44996.418 |     3.389 |     73.61 |    0.4558 |
#> |  295|     44996.405 |    -8.860 |     1181. |   -0.5539 |
#> |    U|     44996.405 |     3.388 |     73.61 |    0.4561 |
#> |  296|     44996.400 |    -8.861 |     1181. |   -0.5539 |
#> |    U|     44996.400 |     3.388 |     73.61 |    0.4561 |
#> |  297|     44996.395 |    -8.863 |     1181. |   -0.5539 |
#> |    U|     44996.395 |     3.387 |     73.61 |    0.4561 |
#> |  298|     44996.387 |    -8.868 |     1181. |   -0.5540 |
#> |    U|     44996.387 |     3.386 |     73.61 |    0.4560 |
#> |  299|     44996.390 |    -8.876 |     1181. |   -0.5541 |
#> |    U|     44996.390 |     3.385 |     73.61 |    0.4559 |
#> |  300|     44996.430 |    -8.868 |     1181. |   -0.5554 |
#> |    U|     44996.430 |     3.387 |     73.61 |    0.4546 |
#> |  301|     44996.382 |    -8.869 |     1181. |   -0.5541 |
#> |    U|     44996.382 |     3.386 |     73.61 |    0.4559 |
#> |  302|     44996.381 |    -8.871 |     1181. |   -0.5542 |
#> |    U|     44996.381 |     3.386 |     73.61 |    0.4558 |
#> |  303|     44996.382 |    -8.869 |     1181. |   -0.5542 |
#> |    U|     44996.382 |     3.386 |     73.61 |    0.4558 |
#> |  304|     44996.441 |    -8.871 |     1181. |   -0.5557 |
#> |    U|     44996.441 |     3.386 |     73.61 |    0.4543 |
#> |  305|     44996.380 |    -8.872 |     1181. |   -0.5542 |
#> |    U|     44996.380 |     3.386 |     73.61 |    0.4558 |
#> |  306|     44996.380 |    -8.873 |     1181. |   -0.5543 |
#> |    U|     44996.380 |     3.385 |     73.61 |    0.4557 |
#> |  307|     44996.381 |    -8.875 |     1181. |   -0.5543 |
#> |    U|     44996.381 |     3.385 |     73.61 |    0.4557 |
#> |  308|     44996.412 |    -8.873 |     1181. |   -0.5534 |
#> |    U|     44996.412 |     3.385 |     73.61 |    0.4566 |
#> |  309|     44996.379 |    -8.872 |     1181. |   -0.5544 |
#> |    U|     44996.379 |     3.386 |     73.61 |    0.4556 |
#> |  310|     44996.379 |    -8.871 |     1181. |   -0.5543 |
#> |    U|     44996.379 |     3.386 |     73.61 |    0.4557 |
#> |  311|     44996.379 |    -8.870 |     1181. |   -0.5542 |
#> |    U|     44996.379 |     3.386 |     73.61 |    0.4558 |
#> |  312|     44996.380 |    -8.871 |     1181. |   -0.5541 |
#> |    U|     44996.380 |     3.386 |     73.61 |    0.4559 |
#> |  313|     44996.379 |    -8.872 |     1181. |   -0.5543 |
#> |    U|     44996.379 |     3.386 |     73.61 |    0.4557 |
#> |  314|     44996.384 |    -8.871 |     1181. |   -0.5540 |
#> |    U|     44996.384 |     3.386 |     73.61 |    0.4560 |
#> |  315|     44996.379 |    -8.871 |     1181. |   -0.5544 |
#> |    U|     44996.379 |     3.386 |     73.61 |    0.4556 |
#> |  316|     44996.378 |    -8.870 |     1181. |   -0.5543 |
#> |    U|     44996.378 |     3.386 |     73.61 |    0.4557 |
#> |  317|     44996.378 |    -8.870 |     1181. |   -0.5543 |
#> |    U|     44996.378 |     3.386 |     73.61 |    0.4557 |
#> |  318|     44996.378 |    -8.869 |     1181. |   -0.5543 |
#> |    U|     44996.378 |     3.386 |     73.61 |    0.4557 |
#> |  319|     44996.378 |    -8.870 |     1181. |   -0.5542 |
#> |    U|     44996.378 |     3.386 |     73.61 |    0.4558 |
#> |  320|     44996.378 |    -8.870 |     1181. |   -0.5543 |
#> |    U|     44996.378 |     3.386 |     73.61 |    0.4557 |
#> |  321|     44996.378 |    -8.870 |     1181. |   -0.5543 |
#> |    U|     44996.378 |     3.386 |     73.61 |    0.4557 |
#> |  322|     44996.377 |    -8.870 |     1181. |   -0.5544 |
#> |    U|     44996.377 |     3.386 |     73.61 |    0.4556 |
#> |  323|     44996.376 |    -8.869 |     1181. |   -0.5544 |
#> |    U|     44996.376 |     3.386 |     73.61 |    0.4556 |
#> |  324|     44996.376 |    -8.869 |     1181. |   -0.5545 |
#> |    U|     44996.376 |     3.386 |     73.61 |    0.4555 |
#> |  325|     44996.375 |    -8.867 |     1181. |   -0.5545 |
#> |    U|     44996.375 |     3.387 |     73.61 |    0.4555 |
#> |  326|     44996.375 |    -8.868 |     1181. |   -0.5546 |
#> |    U|     44996.375 |     3.387 |     73.61 |    0.4554 |
#> |  327|     44996.375 |    -8.868 |     1181. |   -0.5546 |
#> |    U|     44996.375 |     3.387 |     73.61 |    0.4554 |
#> |  328|     44996.372 |    -8.868 |     1181. |   -0.5544 |
#> |    U|     44996.372 |     3.386 |     73.61 |    0.4556 |
#> |  329|     44996.372 |    -8.868 |     1181. |   -0.5542 |
#> |    U|     44996.372 |     3.386 |     73.61 |    0.4558 |
#> |  330|     44996.372 |    -8.868 |     1181. |   -0.5542 |
#> |    U|     44996.372 |     3.387 |     73.61 |    0.4558 |
#> |  331|     44996.372 |    -8.868 |     1181. |   -0.5543 |
#> |    U|     44996.372 |     3.386 |     73.61 |    0.4557 |
#> |  332|     44996.372 |    -8.868 |     1181. |   -0.5543 |
#> |    U|     44996.372 |     3.386 |     73.61 |    0.4557 |
#> |  333|     44996.371 |    -8.869 |     1181. |   -0.5543 |
#> |    U|     44996.371 |     3.386 |     73.61 |    0.4557 |
#> |  334|     44996.371 |    -8.870 |     1181. |   -0.5544 |
#> |    U|     44996.371 |     3.386 |     73.61 |    0.4556 |
#> |  335|     44996.370 |    -8.870 |     1181. |   -0.5543 |
#> |    U|     44996.370 |     3.386 |     73.61 |    0.4557 |
#> |  336|     44996.370 |    -8.870 |     1181. |   -0.5544 |
#> |    U|     44996.370 |     3.386 |     73.61 |    0.4556 |
#> |  337|     44996.370 |    -8.872 |     1181. |   -0.5545 |
#> |    U|     44996.370 |     3.386 |     73.61 |    0.4555 |
#> |  338|     44996.372 |    -8.870 |     1181. |   -0.5540 |
#> |    U|     44996.372 |     3.386 |     73.61 |    0.4560 |
#> |  339|     44996.369 |    -8.870 |     1181. |   -0.5544 |
#> |    U|     44996.369 |     3.386 |     73.61 |    0.4556 |
#> |  340|     44996.367 |    -8.869 |     1181. |   -0.5544 |
#> |    U|     44996.367 |     3.386 |     73.61 |    0.4556 |
#> |  341|     44996.367 |    -8.871 |     1181. |   -0.5545 |
#> |    U|     44996.367 |     3.386 |     73.61 |    0.4555 |
#> |  342|     44996.366 |    -8.869 |     1181. |   -0.5544 |
#> |    U|     44996.366 |     3.386 |     73.61 |    0.4556 |
#> |  343|     44996.364 |    -8.867 |     1181. |   -0.5542 |
#> |    U|     44996.364 |     3.387 |     73.61 |    0.4558 |
#> |  344|     44996.363 |    -8.866 |     1181. |   -0.5545 |
#> |    U|     44996.363 |     3.387 |     73.61 |    0.4555 |
#> |  345|     44996.378 |    -8.859 |     1181. |   -0.5542 |
#> |    U|     44996.378 |     3.388 |     73.61 |    0.4558 |
#> |  346|     44996.438 |    -8.867 |     1181. |   -0.5558 |
#> |    U|     44996.438 |     3.387 |     73.61 |    0.4542 |
#> |  347|     44996.363 |    -8.863 |     1181. |   -0.5541 |
#> |    U|     44996.363 |     3.388 |     73.61 |    0.4559 |
#> |  348|     44996.385 |    -8.867 |     1181. |   -0.5533 |
#> |    U|     44996.385 |     3.387 |     73.61 |    0.4567 |
#> |  349|     44996.361 |    -8.866 |     1181. |   -0.5543 |
#> |    U|     44996.361 |     3.387 |     73.61 |    0.4557 |
#> |  350|     44996.363 |    -8.865 |     1181. |   -0.5542 |
#> |    U|     44996.363 |     3.387 |     73.61 |    0.4558 |
#> |  351|     44996.360 |    -8.867 |     1181. |   -0.5543 |
#> |    U|     44996.360 |     3.387 |     73.61 |    0.4557 |
#> |  352|     44996.360 |    -8.868 |     1181. |   -0.5542 |
#> |    U|     44996.360 |     3.386 |     73.61 |    0.4558 |
#> |  353|     44996.363 |    -8.867 |     1181. |   -0.5540 |
#> |    U|     44996.363 |     3.387 |     73.61 |    0.4560 |
#> |  354|     44996.360 |    -8.868 |     1181. |   -0.5543 |
#> |    U|     44996.360 |     3.387 |     73.61 |    0.4557 |
#> |  355|     44996.359 |    -8.869 |     1181. |   -0.5543 |
#> |    U|     44996.359 |     3.386 |     73.61 |    0.4557 |
#> |  356|     44996.359 |    -8.869 |     1181. |   -0.5543 |
#> |    U|     44996.359 |     3.386 |     73.61 |    0.4557 |
#> |  357|     44996.364 |    -8.868 |     1181. |   -0.5539 |
#> |    U|     44996.364 |     3.386 |     73.61 |    0.4561 |
#> |  358|     44996.359 |    -8.869 |     1181. |   -0.5543 |
#> |    U|     44996.359 |     3.386 |     73.61 |    0.4557 |
#> |  359|     44996.359 |    -8.870 |     1181. |   -0.5543 |
#> |    U|     44996.359 |     3.386 |     73.61 |    0.4557 |
#> |  360|     44996.359 |    -8.872 |     1181. |   -0.5543 |
#> |    U|     44996.359 |     3.386 |     73.61 |    0.4557 |
#> |  361|     44996.362 |    -8.870 |     1181. |   -0.5546 |
#> |    U|     44996.362 |     3.386 |     73.61 |    0.4554 |
#> |  362|     44996.359 |    -8.869 |     1181. |   -0.5543 |
#> |    U|     44996.359 |     3.386 |     73.61 |    0.4557 |
#> |  363|     44996.359 |    -8.870 |     1181. |   -0.5542 |
#> |    U|     44996.359 |     3.386 |     73.61 |    0.4558 |
#> |  364|     44996.359 |    -8.870 |     1181. |   -0.5543 |
#> |    U|     44996.359 |     3.386 |     73.61 |    0.4557 |
#> |  365|     44996.358 |    -8.871 |     1181. |   -0.5543 |
#> |    U|     44996.358 |     3.386 |     73.61 |    0.4557 |
#> |  366|     44996.358 |    -8.872 |     1181. |   -0.5543 |
#> |    U|     44996.358 |     3.386 |     73.61 |    0.4557 |
#> |  367|     44996.358 |    -8.870 |     1181. |   -0.5543 |
#> |    U|     44996.358 |     3.386 |     73.61 |    0.4557 |
#> |  368|     44996.358 |    -8.870 |     1181. |   -0.5543 |
#> |    U|     44996.358 |     3.386 |     73.61 |    0.4557 |
#> |  369|     44996.357 |    -8.870 |     1181. |   -0.5543 |
#> |    U|     44996.357 |     3.386 |     73.61 |    0.4557 |
#> |  370|     44996.356 |    -8.869 |     1181. |   -0.5542 |
#> |    U|     44996.356 |     3.386 |     73.61 |    0.4558 |
#> |  371|     44996.357 |    -8.866 |     1181. |   -0.5542 |
#> |    U|     44996.357 |     3.387 |     73.61 |    0.4558 |
#> |  372|     44996.356 |    -8.868 |     1181. |   -0.5543 |
#> |    U|     44996.356 |     3.386 |     73.61 |    0.4557 |
#> |  373|     44996.355 |    -8.869 |     1181. |   -0.5542 |
#> |    U|     44996.355 |     3.386 |     73.61 |    0.4558 |
#> |  374|     44996.353 |    -8.870 |     1181. |   -0.5542 |
#> |    U|     44996.353 |     3.386 |     73.61 |    0.4558 |
#> |  375|     44996.356 |    -8.876 |     1181. |   -0.5542 |
#> |    U|     44996.356 |     3.385 |     73.61 |    0.4558 |
#> |  376|     44996.396 |    -8.870 |     1181. |   -0.5532 |
#> |    U|     44996.396 |     3.386 |     73.61 |    0.4568 |
#> |  377|     44996.355 |    -8.874 |     1181. |   -0.5544 |
#> |    U|     44996.355 |     3.385 |     73.61 |    0.4556 |
#> |  378|     44996.352 |    -8.870 |     1181. |   -0.5542 |
#> |    U|     44996.352 |     3.386 |     73.61 |    0.4558 |
#> |  379|     44996.350 |    -8.869 |     1181. |   -0.5543 |
#> |    U|     44996.350 |     3.386 |     73.61 |    0.4557 |
#> |  380|     44996.348 |    -8.869 |     1181. |   -0.5542 |
#> |    U|     44996.348 |     3.386 |     73.61 |    0.4558 |
#> |  381|     44996.344 |    -8.867 |     1181. |   -0.5541 |
#> |    U|     44996.344 |     3.387 |     73.61 |    0.4559 |
#> |  382|     44996.338 |    -8.869 |     1181. |   -0.5539 |
#> |    U|     44996.338 |     3.386 |     73.61 |    0.4561 |
#> |  383|     44996.336 |    -8.862 |     1182. |   -0.5534 |
#> |    U|     44996.336 |     3.388 |     73.61 |    0.4566 |
#> |  384|     44996.724 |    -8.866 |     1182. |   -0.5577 |
#> |    U|     44996.724 |     3.387 |     73.61 |    0.4523 |
#> |  385|     44996.320 |    -8.877 |     1182. |   -0.5542 |
#> |    U|     44996.320 |     3.385 |     73.61 |    0.4558 |
#> |  386|     44996.302 |    -8.871 |     1182. |   -0.5541 |
#> |    U|     44996.302 |     3.386 |     73.61 |    0.4559 |
#> |  387|     44996.283 |    -8.868 |     1182. |   -0.5539 |
#> |    U|     44996.283 |     3.386 |     73.61 |    0.4561 |
#> |  388|     44996.241 |    -8.868 |     1182. |   -0.5539 |
#> |    U|     44996.241 |     3.387 |     73.61 |    0.4561 |
#> |  389|     44996.171 |    -8.874 |     1182. |   -0.5538 |
#> |    U|     44996.171 |     3.385 |     73.62 |    0.4562 |
#> |  390|     44996.018 |    -8.865 |     1182. |   -0.5533 |
#> |    U|     44996.018 |     3.387 |     73.62 |    0.4567 |
#> |  391|     44995.772 |    -8.868 |     1182. |   -0.5524 |
#> |    U|     44995.772 |     3.386 |     73.63 |    0.4576 |
#> |  392|     44995.388 |    -8.853 |     1183. |   -0.5505 |
#> |    U|     44995.388 |     3.389 |     73.65 |    0.4595 |
#> |  393|     44995.174 |    -8.836 |     1185. |   -0.5477 |
#> |    U|     44995.174 |     3.393 |     73.68 |    0.4623 |
#> |  394|     44995.174 |    -8.836 |     1185. |   -0.5477 |
#> |    U|     44995.174 |     3.393 |     73.68 |    0.4623 |
#> |  395|     45005.014 |    -8.836 |     1185. |   -0.5348 |
#> |    U|     45005.014 |     3.393 |     73.68 |    0.4752 |
#> |  396|     44994.089 |    -8.833 |     1185. |   -0.5532 |
#> |    U|     44994.089 |     3.394 |     73.68 |    0.4568 |
#> |  397|     44994.218 |    -8.819 |     1185. |   -0.5530 |
#> |    U|     44994.218 |     3.396 |     73.68 |    0.4570 |
#> |  398|     44994.093 |    -8.833 |     1185. |   -0.5532 |
#> |    U|     44994.093 |     3.393 |     73.68 |    0.4568 |
#> |  399|     44994.082 |    -8.833 |     1185. |   -0.5536 |
#> |    U|     44994.082 |     3.393 |     73.68 |    0.4564 |
#> |  400|     44994.058 |    -8.835 |     1185. |   -0.5535 |
#> |    U|     44994.058 |     3.393 |     73.68 |    0.4565 |
#> |  401|     44994.030 |    -8.836 |     1185. |   -0.5538 |
#> |    U|     44994.030 |     3.393 |     73.68 |    0.4562 |
#> |  402|     44994.046 |    -8.832 |     1185. |   -0.5538 |
#> |    U|     44994.046 |     3.394 |     73.68 |    0.4562 |
#> |  403|     44996.204 |    -8.847 |     1185. |   -0.5619 |
#> |    U|     44996.204 |     3.391 |     73.68 |    0.4481 |
#> |  404|     44994.054 |    -8.833 |     1185. |   -0.5537 |
#> |    U|     44994.054 |     3.394 |     73.68 |    0.4563 |
#> |  405|     44994.496 |    -8.837 |     1185. |   -0.5498 |
#> |    U|     44994.496 |     3.393 |     73.68 |    0.4602 |
#> |  406|     44994.015 |    -8.838 |     1185. |   -0.5537 |
#> |    U|     44994.015 |     3.392 |     73.68 |    0.4563 |
#> |  407|     44993.996 |    -8.841 |     1185. |   -0.5535 |
#> |    U|     44993.996 |     3.392 |     73.68 |    0.4565 |
#> |  408|     44993.988 |    -8.841 |     1185. |   -0.5536 |
#> |    U|     44993.988 |     3.392 |     73.68 |    0.4564 |
#> |  409|     44993.993 |    -8.839 |     1185. |   -0.5538 |
#> |    U|     44993.993 |     3.392 |     73.68 |    0.4562 |
#> |  410|     44994.050 |    -8.842 |     1185. |   -0.5552 |
#> |    U|     44994.050 |     3.392 |     73.68 |    0.4548 |
#> |  411|     44993.972 |    -8.844 |     1185. |   -0.5537 |
#> |    U|     44993.972 |     3.391 |     73.68 |    0.4563 |
#> |  412|     44993.948 |    -8.852 |     1185. |   -0.5536 |
#> |    U|     44993.948 |     3.390 |     73.68 |    0.4564 |
#> |  413|     44993.929 |    -8.856 |     1185. |   -0.5537 |
#> |    U|     44993.929 |     3.389 |     73.68 |    0.4563 |
#> |  414|     44993.903 |    -8.859 |     1185. |   -0.5539 |
#> |    U|     44993.903 |     3.388 |     73.68 |    0.4561 |
#> |  415|     44993.857 |    -8.859 |     1185. |   -0.5541 |
#> |    U|     44993.857 |     3.388 |     73.68 |    0.4559 |
#> |  416|     44993.775 |    -8.866 |     1185. |   -0.5545 |
#> |    U|     44993.775 |     3.387 |     73.68 |    0.4555 |
#> |  417|     44993.639 |    -8.870 |     1185. |   -0.5554 |
#> |    U|     44993.639 |     3.386 |     73.69 |    0.4546 |
#> |  418|     44993.520 |    -8.870 |     1186. |   -0.5573 |
#> |    U|     44993.520 |     3.386 |     73.70 |    0.4527 |
#> |  419|     44993.511 |    -8.878 |     1186. |   -0.5576 |
#> |    U|     44993.511 |     3.384 |     73.70 |    0.4524 |
#> |  420|     44993.511 |    -8.878 |     1186. |   -0.5576 |
#> |    U|     44993.511 |     3.384 |     73.70 |    0.4524 |
#> |  421|     44993.511 |    -8.878 |     1186. |   -0.5576 |
#> |    U|     44993.511 |     3.384 |     73.70 |    0.4524 |
#> |  422|     44993.623 |    -8.878 |     1186. |   -0.5581 |
#> |    U|     44993.623 |     3.384 |     73.70 |    0.4519 |
#> |  423|     44993.419 |    -8.878 |     1186. |   -0.5570 |
#> |    U|     44993.419 |     3.384 |     73.70 |    0.4530 |
#> |  424|     44993.294 |    -8.878 |     1186. |   -0.5559 |
#> |    U|     44993.294 |     3.384 |     73.70 |    0.4541 |
#> |  425|     44993.265 |    -8.880 |     1186. |   -0.5553 |
#> |    U|     44993.265 |     3.384 |     73.70 |    0.4547 |
#> |  426|     44993.246 |    -8.878 |     1186. |   -0.5548 |
#> |    U|     44993.246 |     3.384 |     73.70 |    0.4552 |
#> |  427|     44993.225 |    -8.874 |     1186. |   -0.5548 |
#> |    U|     44993.225 |     3.385 |     73.70 |    0.4552 |
#> |  428|     44993.197 |    -8.866 |     1186. |   -0.5545 |
#> |    U|     44993.197 |     3.387 |     73.70 |    0.4555 |
#> |  429|     44993.199 |    -8.854 |     1186. |   -0.5548 |
#> |    U|     44993.199 |     3.389 |     73.70 |    0.4552 |
#> |  430|     44993.208 |    -8.868 |     1186. |   -0.5551 |
#> |    U|     44993.208 |     3.386 |     73.70 |    0.4549 |
#> |  431|     44993.201 |    -8.857 |     1186. |   -0.5548 |
#> |    U|     44993.201 |     3.389 |     73.70 |    0.4552 |
#> |  432|     44993.202 |    -8.866 |     1186. |   -0.5547 |
#> |    U|     44993.202 |     3.387 |     73.70 |    0.4553 |
#> |  433|     44993.195 |    -8.862 |     1186. |   -0.5548 |
#> |    U|     44993.195 |     3.388 |     73.70 |    0.4552 |
#> |  434|     44993.189 |    -8.859 |     1186. |   -0.5546 |
#> |    U|     44993.189 |     3.388 |     73.70 |    0.4554 |
#> |  435|     44993.194 |    -8.860 |     1186. |   -0.5548 |
#> |    U|     44993.194 |     3.388 |     73.70 |    0.4552 |
#> |  436|     44993.290 |    -8.859 |     1186. |   -0.5560 |
#> |    U|     44993.290 |     3.388 |     73.70 |    0.4540 |
#> |  437|     44993.184 |    -8.860 |     1186. |   -0.5543 |
#> |    U|     44993.184 |     3.388 |     73.70 |    0.4557 |
#> |  438|     44993.182 |    -8.860 |     1186. |   -0.5543 |
#> |    U|     44993.182 |     3.388 |     73.70 |    0.4557 |
#> |  439|     44993.182 |    -8.863 |     1186. |   -0.5543 |
#> |    U|     44993.182 |     3.387 |     73.70 |    0.4557 |
#> |  440|     44993.219 |    -8.860 |     1186. |   -0.5532 |
#> |    U|     44993.219 |     3.388 |     73.70 |    0.4568 |
#> |  441|     44993.183 |    -8.862 |     1186. |   -0.5543 |
#> |    U|     44993.183 |     3.388 |     73.70 |    0.4557 |
#> |  442|     44993.181 |    -8.859 |     1186. |   -0.5542 |
#> |    U|     44993.181 |     3.388 |     73.70 |    0.4558 |
#> |  443|     44993.182 |    -8.858 |     1186. |   -0.5542 |
#> |    U|     44993.182 |     3.389 |     73.70 |    0.4558 |
#> |  444|     44993.181 |    -8.858 |     1186. |   -0.5543 |
#> |    U|     44993.181 |     3.388 |     73.70 |    0.4557 |
#> |  445|     44993.181 |    -8.858 |     1186. |   -0.5542 |
#> |    U|     44993.181 |     3.388 |     73.70 |    0.4558 |
#> |  446|     44993.180 |    -8.858 |     1186. |   -0.5543 |
#> |    U|     44993.180 |     3.389 |     73.70 |    0.4557 |
#> |  447|     44993.178 |    -8.857 |     1186. |   -0.5542 |
#> |    U|     44993.178 |     3.389 |     73.70 |    0.4558 |
#> |  448|     44993.176 |    -8.854 |     1186. |   -0.5542 |
#> |    U|     44993.176 |     3.389 |     73.70 |    0.4558 |
#> |  449|     44993.173 |    -8.854 |     1186. |   -0.5542 |
#> |    U|     44993.173 |     3.389 |     73.70 |    0.4558 |
#> |  450|     44993.167 |    -8.858 |     1186. |   -0.5543 |
#> |    U|     44993.167 |     3.388 |     73.70 |    0.4557 |
#> |  451|     44993.156 |    -8.856 |     1186. |   -0.5543 |
#> |    U|     44993.156 |     3.389 |     73.70 |    0.4557 |
#> |  452|     44993.133 |    -8.856 |     1186. |   -0.5541 |
#> |    U|     44993.133 |     3.389 |     73.70 |    0.4559 |
#> |  453|     44993.088 |    -8.857 |     1186. |   -0.5540 |
#> |    U|     44993.088 |     3.389 |     73.70 |    0.4560 |
#> |  454|     44993.000 |    -8.856 |     1186. |   -0.5538 |
#> |    U|     44993.000 |     3.389 |     73.71 |    0.4562 |
#> |  455|     44992.843 |    -8.844 |     1187. |   -0.5533 |
#> |    U|     44992.843 |     3.391 |     73.71 |    0.4567 |
#> |  456|     44992.527 |    -8.850 |     1187. |   -0.5525 |
#> |    U|     44992.527 |     3.390 |     73.72 |    0.4575 |
#> |  457|     44992.037 |    -8.836 |     1188. |   -0.5508 |
#> |    U|     44992.037 |     3.393 |     73.74 |    0.4592 |
#> |  458|     44991.275 |    -8.821 |     1190. |   -0.5481 |
#> |    U|     44991.275 |     3.396 |     73.79 |    0.4619 |
#> |  459|     44990.397 |    -8.816 |     1190. |   -0.5531 |
#> |    U|     44990.397 |     3.397 |     73.79 |    0.4569 |
#> |  460|     44989.048 |    -8.801 |     1192. |   -0.5526 |
#> |    U|     44989.048 |     3.400 |     73.83 |    0.4574 |
#> |  461|     44986.062 |    -8.826 |     1197. |   -0.5521 |
#> |    U|     44986.062 |     3.395 |     73.92 |    0.4579 |
#> |  462|     44980.631 |    -8.792 |     1205. |   -0.5504 |
#> |    U|     44980.631 |     3.402 |     74.09 |    0.4596 |
#> |  463|     44970.527 |    -8.752 |     1222. |   -0.5472 |
#> |    U|     44970.527 |     3.410 |     74.43 |    0.4628 |
#> |  464|     44970.482 |    -8.727 |     1222. |   -0.5470 |
#> |    U|     44970.482 |     3.415 |     74.43 |    0.4630 |
#> |  465|     44961.215 |    -8.671 |     1239. |   -0.5437 |
#> |    U|     44961.215 |     3.426 |     74.77 |    0.4663 |
#> |  466|     44945.285 |    -8.535 |     1274. |   -0.5368 |
#> |    U|     44945.285 |     3.453 |     75.45 |    0.4732 |
#> |  467|     44922.509 |    -8.308 |     1342. |   -0.5234 |
#> |    U|     44922.509 |     3.499 |     76.82 |    0.4866 |
#> |  468|     44911.933 |    -8.166 |     1439. |   -0.5053 |
#> |    U|     44911.933 |     3.527 |     78.76 |    0.5047 |
#> |  469|     44933.010 |    -8.078 |     1441. |   -0.4936 |
#> |    U|     44933.010 |     3.544 |     78.81 |    0.5164 |
#> |  470| 5.1905208e+18 |    -5.867 |     1439. |    -1.010 |
#> |    U| 5.1905208e+18 |     3.987 |     78.76 | 1.490e-08 |
#> |  471|     48317.260 |    -10.47 |     1439. |  -0.01000 |
#> |    U|     48317.260 |     3.067 |     78.76 |     1.000 |
#> |  472| 3.1049194e+18 |    -9.225 |     1439. |    -1.010 |
#> |    U| 3.1049194e+18 |     3.315 |     78.76 | 1.490e-08 |
#> |  473|     47416.382 |    -8.030 |     1439. |  -0.01000 |
#> |    U|     47416.382 |     3.554 |     78.76 |     1.000 |
#> |  474|     44977.565 |    -8.177 |     1438. |   -0.5968 |
#> |    U|     44977.565 |     3.525 |     78.75 |    0.4132 |
#> |  475|     46941.791 |    -8.513 |     1439. |   -0.1213 |
#> |    U|     46941.791 |     3.458 |     78.76 |    0.8887 |
#> |  476|     44889.213 |    -7.936 |     1439. |   -0.5558 |
#> |    U|     44889.213 |     3.573 |     78.76 |    0.4542 |
#> |  477|     45616.670 |    -8.072 |     1439. |   -0.3335 |
#> |    U|     45616.670 |     3.546 |     78.76 |    0.6765 |
#> |  478|     44884.530 |    -7.944 |     1439. |   -0.5524 |
#> |    U|     44884.530 |     3.571 |     78.76 |    0.4576 |
#> |  479|     44873.517 |    -8.023 |     1439. |   -0.5396 |
#> |    U|     44873.517 |     3.556 |     78.76 |    0.4704 |
#> |  480|     44887.344 |    -8.083 |     1439. |   -0.5633 |
#> |    U|     44887.344 |     3.543 |     78.76 |    0.4467 |
#> |  481|     45023.269 |    -8.000 |     1439. |   -0.6006 |
#> |    U|     45023.269 |     3.560 |     78.76 |    0.4094 |
#> |  482|     44873.386 |    -8.032 |     1439. |   -0.5429 |
#> |    U|     44873.386 |     3.554 |     78.76 |    0.4671 |
#> |  483|     44880.479 |    -8.058 |     1439. |   -0.5244 |
#> |    U|     44880.479 |     3.549 |     78.76 |    0.4856 |
#> |  484|     44876.626 |    -8.022 |     1439. |   -0.5299 |
#> |    U|     44876.626 |     3.556 |     78.76 |    0.4801 |
#> |  485|     44876.804 |    -8.019 |     1439. |   -0.5497 |
#> |    U|     44876.804 |     3.556 |     78.76 |    0.4603 |
#> |  486|     44875.632 |    -8.028 |     1439. |   -0.5487 |
#> |    U|     44875.632 |     3.554 |     78.76 |    0.4613 |
#> |  487|     44872.992 |    -8.036 |     1439. |   -0.5397 |
#> |    U|     44872.992 |     3.553 |     78.76 |    0.4703 |
#> |  488|     44873.327 |    -8.039 |     1439. |   -0.5367 |
#> |    U|     44873.327 |     3.552 |     78.76 |    0.4733 |
#> |  489|     44873.013 |    -8.039 |     1439. |   -0.5426 |
#> |    U|     44873.013 |     3.552 |     78.76 |    0.4674 |
#> |  490|     44872.877 |    -8.039 |     1439. |   -0.5405 |
#> |    U|     44872.877 |     3.552 |     78.76 |    0.4695 |
#> |  491|     44872.908 |    -8.042 |     1439. |   -0.5426 |
#> |    U|     44872.908 |     3.552 |     78.76 |    0.4674 |
#> |  492|     44872.880 |    -8.041 |     1439. |   -0.5391 |
#> |    U|     44872.880 |     3.552 |     78.76 |    0.4709 |
#> |  493|     44872.808 |    -8.041 |     1439. |   -0.5405 |
#> |    U|     44872.808 |     3.552 |     78.76 |    0.4695 |
#> |  494|     44872.704 |    -8.044 |     1439. |   -0.5397 |
#> |    U|     44872.704 |     3.551 |     78.76 |    0.4703 |
#> |  495|     44872.630 |    -8.048 |     1439. |   -0.5392 |
#> |    U|     44872.630 |     3.551 |     78.76 |    0.4708 |
#> |  496|     44872.620 |    -8.049 |     1439. |   -0.5388 |
#> |    U|     44872.620 |     3.550 |     78.76 |    0.4712 |
#> |  497|     44872.627 |    -8.050 |     1439. |   -0.5386 |
#> |    U|     44872.627 |     3.550 |     78.76 |    0.4714 |
#> |  498|     44872.544 |    -8.049 |     1439. |   -0.5396 |
#> |    U|     44872.544 |     3.550 |     78.76 |    0.4704 |
#> |  499|     44872.491 |    -8.050 |     1439. |   -0.5403 |
#> |    U|     44872.491 |     3.550 |     78.76 |    0.4697 |
#> |  500|     44872.447 |    -8.051 |     1439. |   -0.5414 |
#> |    U|     44872.447 |     3.550 |     78.76 |    0.4686 |
#> |  501|     44872.447 |    -8.052 |     1439. |   -0.5419 |
#> |    U|     44872.447 |     3.550 |     78.76 |    0.4681 |
#> |  502|     44872.474 |    -8.050 |     1439. |   -0.5415 |
#> |    U|     44872.474 |     3.550 |     78.76 |    0.4685 |
#> |  503|     44872.413 |    -8.052 |     1439. |   -0.5413 |
#> |    U|     44872.413 |     3.550 |     78.76 |    0.4687 |
#> |  504|     44872.357 |    -8.054 |     1439. |   -0.5415 |
#> |    U|     44872.357 |     3.549 |     78.76 |    0.4685 |
#> |  505|     44872.271 |    -8.057 |     1439. |   -0.5421 |
#> |    U|     44872.271 |     3.549 |     78.76 |    0.4679 |
#> |  506|     44872.158 |    -8.060 |     1439. |   -0.5418 |
#> |    U|     44872.158 |     3.548 |     78.76 |    0.4682 |
#> |  507|     44871.974 |    -8.066 |     1439. |   -0.5425 |
#> |    U|     44871.974 |     3.547 |     78.76 |    0.4675 |
#> |  508|     44871.530 |    -8.080 |     1439. |   -0.5416 |
#> |    U|     44871.530 |     3.544 |     78.76 |    0.4684 |
#> |  509|     44870.942 |    -8.105 |     1439. |   -0.5408 |
#> |    U|     44870.942 |     3.539 |     78.76 |    0.4692 |
#> |  510|     44869.984 |    -8.160 |     1439. |   -0.5428 |
#> |    U|     44869.984 |     3.528 |     78.76 |    0.4672 |
#> |  511|     44869.708 |    -8.199 |     1439. |   -0.5445 |
#> |    U|     44869.708 |     3.520 |     78.76 |    0.4655 |
#> |  512|     44869.759 |    -8.216 |     1439. |   -0.5468 |
#> |    U|     44869.759 |     3.517 |     78.76 |    0.4632 |
#> |  513|     44877.173 |    -8.199 |     1439. |   -0.5293 |
#> |    U|     44877.173 |     3.520 |     78.76 |    0.4807 |
#> |  514|     44869.788 |    -8.210 |     1439. |   -0.5469 |
#> |    U|     44869.788 |     3.518 |     78.76 |    0.4631 |
#> |  515|     44870.413 |    -8.197 |     1439. |   -0.5496 |
#> |    U|     44870.413 |     3.521 |     78.76 |    0.4604 |
#> |  516|     44869.742 |    -8.190 |     1439. |   -0.5453 |
#> |    U|     44869.742 |     3.522 |     78.76 |    0.4647 |
#> |  517|     44870.044 |    -8.199 |     1439. |   -0.5482 |
#> |    U|     44870.044 |     3.520 |     78.76 |    0.4618 |
#> |  518|     44869.699 |    -8.200 |     1439. |   -0.5449 |
#> |    U|     44869.699 |     3.520 |     78.76 |    0.4651 |
#> |  519|     44869.710 |    -8.195 |     1439. |   -0.5448 |
#> |    U|     44869.710 |     3.521 |     78.76 |    0.4652 |
#> |  520|     44869.784 |    -8.200 |     1439. |   -0.5434 |
#> |    U|     44869.784 |     3.520 |     78.76 |    0.4666 |
#> |  521|     44869.698 |    -8.201 |     1439. |   -0.5449 |
#> |    U|     44869.698 |     3.520 |     78.76 |    0.4651 |
#> |  522|     44869.697 |    -8.202 |     1439. |   -0.5449 |
#> |    U|     44869.697 |     3.520 |     78.76 |    0.4651 |
#> |  523|     44869.696 |    -8.202 |     1439. |   -0.5451 |
#> |    U|     44869.696 |     3.520 |     78.76 |    0.4649 |
#> |  524|     44869.695 |    -8.204 |     1439. |   -0.5451 |
#> |    U|     44869.695 |     3.519 |     78.76 |    0.4649 |
#> |  525|     44869.693 |    -8.206 |     1439. |   -0.5452 |
#> |    U|     44869.693 |     3.519 |     78.76 |    0.4648 |
#> |  526|     44869.692 |    -8.207 |     1439. |   -0.5453 |
#> |    U|     44869.692 |     3.519 |     78.76 |    0.4647 |
#> |  527|     44869.693 |    -8.203 |     1439. |   -0.5452 |
#> |    U|     44869.693 |     3.519 |     78.76 |    0.4648 |
#> |  528|     44869.692 |    -8.208 |     1439. |   -0.5450 |
#> |    U|     44869.692 |     3.519 |     78.76 |    0.4650 |
#> |  529|     44869.692 |    -8.210 |     1439. |   -0.5453 |
#> |    U|     44869.692 |     3.518 |     78.76 |    0.4647 |
#> |  530|     44869.708 |    -8.210 |     1439. |   -0.5446 |
#> |    U|     44869.708 |     3.518 |     78.76 |    0.4654 |
#> |  531|     44869.691 |    -8.209 |     1439. |   -0.5452 |
#> |    U|     44869.691 |     3.518 |     78.76 |    0.4648 |
#> |  532|     44869.691 |    -8.208 |     1439. |   -0.5452 |
#> |    U|     44869.691 |     3.519 |     78.76 |    0.4648 |
#> |  533|     44869.690 |    -8.207 |     1439. |   -0.5452 |
#> |    U|     44869.690 |     3.519 |     78.76 |    0.4648 |
#> |  534|     44869.689 |    -8.208 |     1439. |   -0.5453 |
#> |    U|     44869.689 |     3.518 |     78.76 |    0.4647 |
#> |  535|     44869.687 |    -8.208 |     1439. |   -0.5454 |
#> |    U|     44869.687 |     3.519 |     78.76 |    0.4646 |
#> |  536|     44869.688 |    -8.211 |     1439. |   -0.5456 |
#> |    U|     44869.688 |     3.518 |     78.76 |    0.4644 |
#> |  537|     44869.902 |    -8.208 |     1439. |   -0.5478 |
#> |    U|     44869.902 |     3.518 |     78.76 |    0.4622 |
#> |  538|     44869.684 |    -8.207 |     1439. |   -0.5451 |
#> |    U|     44869.684 |     3.519 |     78.76 |    0.4649 |
#> |  539|     44869.683 |    -8.209 |     1439. |   -0.5452 |
#> |    U|     44869.683 |     3.518 |     78.76 |    0.4648 |
#> |  540|     44869.682 |    -8.210 |     1439. |   -0.5452 |
#> |    U|     44869.682 |     3.518 |     78.76 |    0.4648 |
#> |  541|     44869.678 |    -8.210 |     1439. |   -0.5452 |
#> |    U|     44869.678 |     3.518 |     78.76 |    0.4648 |
#> |  542|     44869.672 |    -8.210 |     1439. |   -0.5453 |
#> |    U|     44869.672 |     3.518 |     78.76 |    0.4647 |
#> |  543|     44869.664 |    -8.214 |     1439. |   -0.5456 |
#> |    U|     44869.664 |     3.517 |     78.76 |    0.4644 |
#> |  544|     44869.655 |    -8.216 |     1439. |   -0.5458 |
#> |    U|     44869.655 |     3.517 |     78.76 |    0.4642 |
#> |  545|     44869.616 |    -8.211 |     1439. |   -0.5449 |
#> |    U|     44869.616 |     3.518 |     78.77 |    0.4651 |
#> |  546|     44869.564 |    -8.217 |     1439. |   -0.5451 |
#> |    U|     44869.564 |     3.517 |     78.77 |    0.4649 |
#> |  547|     44869.492 |    -8.228 |     1440. |   -0.5452 |
#> |    U|     44869.492 |     3.514 |     78.78 |    0.4648 |
#> |  548|     44869.241 |    -8.227 |     1441. |   -0.5460 |
#> |    U|     44869.241 |     3.515 |     78.79 |    0.4640 |
#> |  549|     44868.906 |    -8.240 |     1442. |   -0.5472 |
#> |    U|     44868.906 |     3.512 |     78.83 |    0.4628 |
#> |  550|     44868.182 |    -8.255 |     1446. |   -0.5473 |
#> |    U|     44868.182 |     3.509 |     78.89 |    0.4627 |
#> |  551|     44866.491 |    -8.248 |     1452. |   -0.5448 |
#> |    U|     44866.491 |     3.510 |     79.02 |    0.4652 |
#> |  552|     44863.519 |    -8.225 |     1465. |   -0.5417 |
#> |    U|     44863.519 |     3.515 |     79.29 |    0.4683 |
#> |  553|     44856.768 |    -8.182 |     1492. |   -0.5449 |
#> |    U|     44856.768 |     3.524 |     79.81 |    0.4651 |
#> |  554|     44850.613 |    -8.177 |     1544. |   -0.5470 |
#> |    U|     44850.613 |     3.525 |     80.87 |    0.4630 |
#> |  555|     44841.666 |    -8.004 |     1591. |   -0.5432 |
#> |    U|     44841.666 |     3.559 |     81.80 |    0.4668 |
#> |  556|     44834.896 |    -7.757 |     1665. |   -0.5332 |
#> |    U|     44834.896 |     3.609 |     83.28 |    0.4768 |
#> |  557|     44835.798 |    -7.704 |     1684. |   -0.5272 |
#> |    U|     44835.798 |     3.619 |     83.67 |    0.4828 |
#> |  558|     329887.64 |     11.83 |     1665. |  -0.01000 |
#> |    U|     329887.64 |     7.527 |     83.28 |     1.000 |
#> |  559| 1.0382400e+19 |    -25.80 |     1673. |    -1.010 |
#> |    U| 1.0382400e+19 | 1.490e-08 |     83.43 | 1.490e-08 |
#> |  560|     52225.770 |    -17.54 |     1665. |  -0.01000 |
#> |    U|     52225.770 |     1.652 |     83.28 |     1.000 |
#> |  561|     47585.864 |    -1.582 |     1672. |  -0.01000 |
#> |    U|     47585.864 |     4.844 |     83.43 |     1.000 |
#> |  562| 3.2013186e+18 |    -11.30 |     1662. |    -1.010 |
#> |    U| 3.2013186e+18 |     2.901 |     83.21 | 1.490e-08 |
#> |  563|     46880.047 |    -5.853 |     1660. |  -0.01000 |
#> |    U|     46880.047 |     3.989 |     83.19 |     1.000 |
#> |  564| 4.6911755e+18 |    -5.856 |     1665. |    -1.010 |
#> |    U| 4.6911755e+18 |     3.989 |     83.28 | 1.490e-08 |
#> |  565|     48160.100 |    -10.09 |     1664. |  -0.01000 |
#> |    U|     48160.100 |     3.143 |     83.27 |     1.000 |
#> |  566| 3.3090739e+18 |    -8.487 |     1666. |    -1.010 |
#> |    U| 3.3090739e+18 |     3.463 |     83.30 | 1.490e-08 |
#> |  567|     47385.859 |    -7.956 |     1664. |  -0.01000 |
#> |    U|     47385.859 |     3.569 |     83.26 |     1.000 |
#> |  568|     47206.555 |    -7.645 |     1665. |  -0.02581 |
#> |    U|     47206.555 |     3.631 |     83.28 |    0.9842 |
#> |  569|     46377.866 |    -8.172 |     1665. |   -0.2011 |
#> |    U|     46377.866 |     3.526 |     83.27 |    0.8089 |
#> |  570|     44860.674 |    -7.978 |     1665. |   -0.5630 |
#> |    U|     44860.674 |     3.565 |     83.27 |    0.4470 |
#> |  571|     45684.640 |    -7.723 |     1665. |   -0.3040 |
#> |    U|     45684.640 |     3.615 |     83.27 |    0.7060 |
#> |  572|     44885.785 |    -7.608 |     1665. |   -0.5704 |
#> |    U|     44885.785 |     3.638 |     83.28 |    0.4396 |
#> |  573|     45201.714 |    -7.764 |     1665. |   -0.4019 |
#> |    U|     45201.714 |     3.607 |     83.28 |    0.6081 |
#> |  574|     44859.348 |    -7.802 |     1665. |   -0.5630 |
#> |    U|     44859.348 |     3.600 |     83.28 |    0.4470 |
#> |  575|     44848.964 |    -7.706 |     1665. |   -0.5113 |
#> |    U|     44848.964 |     3.619 |     83.28 |    0.4987 |
#> |  576|     44863.913 |    -7.764 |     1665. |   -0.5649 |
#> |    U|     44863.913 |     3.607 |     83.28 |    0.4451 |
#> |  577|     44864.867 |    -7.776 |     1665. |   -0.5655 |
#> |    U|     44864.867 |     3.605 |     83.28 |    0.4445 |
#> |  578|     44838.121 |    -7.774 |     1665. |   -0.5260 |
#> |    U|     44838.121 |     3.605 |     83.28 |    0.4840 |
#> |  579|     44840.332 |    -7.744 |     1665. |   -0.5211 |
#> |    U|     44840.332 |     3.611 |     83.28 |    0.4889 |
#> |  580|     44834.528 |    -7.747 |     1665. |   -0.5355 |
#> |    U|     44834.528 |     3.611 |     83.28 |    0.4745 |
#> |  581|     44834.618 |    -7.747 |     1665. |   -0.5337 |
#> |    U|     44834.618 |     3.611 |     83.28 |    0.4763 |
#> |  582|     44834.868 |    -7.750 |     1665. |   -0.5385 |
#> |    U|     44834.868 |     3.610 |     83.28 |    0.4715 |
#> |  583|     44834.636 |    -7.749 |     1665. |   -0.5340 |
#> |    U|     44834.636 |     3.610 |     83.28 |    0.4760 |
#> |  584|     44834.656 |    -7.748 |     1665. |   -0.5373 |
#> |    U|     44834.656 |     3.610 |     83.28 |    0.4727 |
#> |  585|     44834.546 |    -7.745 |     1665. |   -0.5366 |
#> |    U|     44834.546 |     3.611 |     83.28 |    0.4734 |
#> |  586|     44834.549 |    -7.747 |     1665. |   -0.5344 |
#> |    U|     44834.549 |     3.611 |     83.28 |    0.4756 |
#> |  587|     44834.526 |    -7.747 |     1665. |   -0.5355 |
#> |    U|     44834.526 |     3.611 |     83.28 |    0.4745 |
#> |  588|     44834.527 |    -7.747 |     1665. |   -0.5355 |
#> |    U|     44834.527 |     3.611 |     83.28 |    0.4745 |
#> |  589|     44834.529 |    -7.747 |     1665. |   -0.5354 |
#> |    U|     44834.529 |     3.611 |     83.28 |    0.4746 |
#> |  590|     44834.524 |    -7.747 |     1665. |   -0.5355 |
#> |    U|     44834.524 |     3.611 |     83.28 |    0.4745 |
#> |  591|     44834.519 |    -7.747 |     1665. |   -0.5355 |
#> |    U|     44834.519 |     3.611 |     83.28 |    0.4745 |
#> |  592|     44834.512 |    -7.746 |     1665. |   -0.5356 |
#> |    U|     44834.512 |     3.611 |     83.28 |    0.4744 |
#> |  593|     44834.505 |    -7.746 |     1665. |   -0.5358 |
#> |    U|     44834.505 |     3.611 |     83.28 |    0.4742 |
#> |  594|     44834.491 |    -7.745 |     1665. |   -0.5357 |
#> |    U|     44834.491 |     3.611 |     83.28 |    0.4743 |
#> |  595|     44834.456 |    -7.743 |     1665. |   -0.5351 |
#> |    U|     44834.456 |     3.611 |     83.28 |    0.4749 |
#> |  596|     44834.410 |    -7.741 |     1665. |   -0.5349 |
#> |    U|     44834.410 |     3.612 |     83.28 |    0.4751 |
#> |  597|     44834.355 |    -7.736 |     1665. |   -0.5341 |
#> |    U|     44834.355 |     3.613 |     83.28 |    0.4759 |
#> |  598|     44834.269 |    -7.730 |     1665. |   -0.5338 |
#> |    U|     44834.269 |     3.614 |     83.28 |    0.4762 |
#> |  599|     44834.404 |    -7.717 |     1665. |   -0.5312 |
#> |    U|     44834.404 |     3.617 |     83.28 |    0.4788 |
#> |  600|     44834.292 |    -7.732 |     1665. |   -0.5341 |
#> |    U|     44834.292 |     3.614 |     83.28 |    0.4759 |
#> |  601|     44834.165 |    -7.726 |     1665. |   -0.5353 |
#> |    U|     44834.165 |     3.615 |     83.28 |    0.4747 |
#> |  602|     44834.120 |    -7.721 |     1665. |   -0.5338 |
#> |    U|     44834.120 |     3.616 |     83.28 |    0.4762 |
#> |  603|     44833.995 |    -7.714 |     1665. |   -0.5344 |
#> |    U|     44833.995 |     3.617 |     83.28 |    0.4756 |
#> |  604|     44833.863 |    -7.702 |     1665. |   -0.5343 |
#> |    U|     44833.863 |     3.620 |     83.28 |    0.4757 |
#> |  605|     44833.666 |    -7.679 |     1665. |   -0.5341 |
#> |    U|     44833.666 |     3.624 |     83.28 |    0.4759 |
#> |  606|     44833.571 |    -7.648 |     1665. |   -0.5335 |
#> |    U|     44833.571 |     3.631 |     83.28 |    0.4765 |
#> |  607|     44833.571 |    -7.647 |     1665. |   -0.5335 |
#> |    U|     44833.571 |     3.631 |     83.28 |    0.4765 |
#> |  608|     44834.051 |    -7.647 |     1665. |   -0.5288 |
#> |    U|     44834.051 |     3.631 |     83.28 |    0.4812 |
#> |  609|     44833.565 |    -7.647 |     1665. |   -0.5334 |
#> |    U|     44833.565 |     3.631 |     83.28 |    0.4766 |
#> |  610|     44833.588 |    -7.645 |     1665. |   -0.5338 |
#> |    U|     44833.588 |     3.631 |     83.28 |    0.4762 |
#> |  611|     44833.611 |    -7.647 |     1665. |   -0.5342 |
#> |    U|     44833.611 |     3.631 |     83.28 |    0.4758 |
#> |  612|     44833.557 |    -7.647 |     1665. |   -0.5330 |
#> |    U|     44833.557 |     3.631 |     83.28 |    0.4770 |
#> |  613|     44833.557 |    -7.646 |     1665. |   -0.5330 |
#> |    U|     44833.557 |     3.631 |     83.28 |    0.4770 |
#> |  614|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  615|     44833.556 |    -7.646 |     1665. |   -0.5329 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4771 |
#> |  616|     44833.559 |    -7.646 |     1665. |   -0.5325 |
#> |    U|     44833.559 |     3.631 |     83.28 |    0.4775 |
#> |  617|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  618|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  619|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  620|     44833.557 |    -7.646 |     1665. |   -0.5329 |
#> |    U|     44833.557 |     3.631 |     83.28 |    0.4771 |
#> |  621|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  622|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  623|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  624|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  625|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  626|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  627|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  628|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  629|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  630|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  631|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  632|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  633|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  634|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  635|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  636|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  637|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  638|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  639|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  640|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  641|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  642|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  643|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  644|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  645|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  646|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  647|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  648|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  649|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  650|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  651|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  652|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  653|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  654|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  655|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  656|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  657|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  658|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  659|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  660|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  661|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  662|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  663|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  664|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  665|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  666|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  667|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  668|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  669|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  670|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  671|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  672|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  673|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  674|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  675|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  676|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  677|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  678|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  679|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  680|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  681|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  682|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  683|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  684|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  685|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  686|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  687|     44833.556 |    -7.645 |     1665. |   -0.5327 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4773 |
#> |  688|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  689|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  690|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  691|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  692|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  693|     44833.556 |    -7.645 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  694|     44833.556 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.556 |     3.631 |     83.28 |    0.4772 |
#> |  695|     44833.555 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.555 |     3.631 |     83.28 |    0.4772 |
#> |  696|     44833.554 |    -7.646 |     1665. |   -0.5328 |
#> |    U|     44833.554 |     3.631 |     83.28 |    0.4772 |
#> |  697|     44833.553 |    -7.647 |     1665. |   -0.5329 |
#> |    U|     44833.553 |     3.631 |     83.28 |    0.4771 |
#> |  698|     44833.551 |    -7.649 |     1665. |   -0.5329 |
#> |    U|     44833.551 |     3.630 |     83.28 |    0.4771 |
#> |  699|     44833.548 |    -7.652 |     1665. |   -0.5330 |
#> |    U|     44833.548 |     3.630 |     83.29 |    0.4770 |
#> |  700|     44833.546 |    -7.652 |     1665. |   -0.5330 |
#> |    U|     44833.546 |     3.630 |     83.29 |    0.4770 |
#> |  701|     44833.546 |    -7.653 |     1666. |   -0.5333 |
#> |    U|     44833.546 |     3.629 |     83.29 |    0.4767 |
#> |  702|     44833.543 |    -7.653 |     1666. |   -0.5331 |
#> |    U|     44833.543 |     3.629 |     83.30 |    0.4769 |
#> |  703|     44833.545 |    -7.655 |     1666. |   -0.5330 |
#> |    U|     44833.545 |     3.629 |     83.30 |    0.4770 |
#> |  704|     44849.481 |    -7.718 |     1666. |   -0.5114 |
#> |    U|     44849.481 |     3.616 |     83.30 |    0.4986 |
#> |  705|     44833.540 |    -7.653 |     1666. |   -0.5331 |
#> |    U|     44833.540 |     3.630 |     83.30 |    0.4769 |
#> |  706|     44833.536 |    -7.652 |     1666. |   -0.5332 |
#> |    U|     44833.536 |     3.630 |     83.30 |    0.4768 |
#> |  707|     44833.536 |    -7.652 |     1666. |   -0.5333 |
#> |    U|     44833.536 |     3.630 |     83.30 |    0.4767 |
#> |  708|     44833.535 |    -7.653 |     1666. |   -0.5333 |
#> |    U|     44833.535 |     3.629 |     83.30 |    0.4767 |
#> |  709|     44833.537 |    -7.654 |     1667. |   -0.5335 |
#> |    U|     44833.537 |     3.629 |     83.31 |    0.4765 |
#> |  710|     45751.439 |    -7.654 |     1666. |   -0.6651 |
#> |    U|     45751.439 |     3.629 |     83.30 |    0.3449 |
#> |  711|     44918.255 |    -7.623 |     1666. |   -0.4742 |
#> |    U|     44918.255 |     3.635 |     83.31 |    0.5358 |
#> |  712|     44833.833 |    -7.605 |     1666. |   -0.5342 |
#> |    U|     44833.833 |     3.639 |     83.30 |    0.4758 |
#> |  713|     44861.613 |    -7.662 |     1666. |   -0.5013 |
#> |    U|     44861.613 |     3.628 |     83.30 |    0.5087 |
#> |  714|     44833.535 |    -7.653 |     1666. |   -0.5333 |
#> |    U|     44833.535 |     3.629 |     83.31 |    0.4767 |
#> |  715|     44836.595 |    -7.644 |     1666. |   -0.5225 |
#> |    U|     44836.595 |     3.631 |     83.31 |    0.4875 |
#> |  716|     44841.411 |    -7.653 |     1666. |   -0.5165 |
#> |    U|     44841.411 |     3.629 |     83.31 |    0.4935 |
#> |  717|     44834.059 |    -7.669 |     1666. |   -0.5295 |
#> |    U|     44834.059 |     3.626 |     83.31 |    0.4805 |
#> |  718|     44835.949 |    -7.654 |     1666. |   -0.5418 |
#> |    U|     44835.949 |     3.629 |     83.31 |    0.4682 |
#> |  719|     44833.543 |    -7.656 |     1666. |   -0.5327 |
#> |    U|     44833.543 |     3.629 |     83.31 |    0.4773 |
#> |  720|     44833.547 |    -7.649 |     1666. |   -0.5338 |
#> |    U|     44833.547 |     3.630 |     83.31 |    0.4762 |
#> |  721|     44833.526 |    -7.650 |     1666. |   -0.5330 |
#> |    U|     44833.526 |     3.630 |     83.31 |    0.4770 |
#> |  722|     44833.523 |    -7.647 |     1666. |   -0.5329 |
#> |    U|     44833.523 |     3.631 |     83.31 |    0.4771 |
#> |  723|     44833.523 |    -7.647 |     1666. |   -0.5330 |
#> |    U|     44833.523 |     3.631 |     83.31 |    0.4770 |
#> |  724|     44833.521 |    -7.645 |     1666. |   -0.5327 |
#> |    U|     44833.521 |     3.631 |     83.31 |    0.4773 |
#> |  725|     44833.521 |    -7.645 |     1666. |   -0.5329 |
#> |    U|     44833.521 |     3.631 |     83.31 |    0.4771 |
#> |  726|     44833.537 |    -7.645 |     1666. |   -0.5321 |
#> |    U|     44833.537 |     3.631 |     83.31 |    0.4779 |
#> |  727|     44833.521 |    -7.645 |     1666. |   -0.5329 |
#> |    U|     44833.521 |     3.631 |     83.31 |    0.4771 |
#> |  728|     44833.526 |    -7.645 |     1666. |   -0.5332 |
#> |    U|     44833.526 |     3.631 |     83.31 |    0.4768 |
#> |  729|     44833.520 |    -7.644 |     1666. |   -0.5328 |
#> |    U|     44833.520 |     3.631 |     83.31 |    0.4772 |
#> |  730|     44833.520 |    -7.644 |     1666. |   -0.5328 |
#> |    U|     44833.520 |     3.631 |     83.31 |    0.4772 |
#> |  731|     44833.531 |    -7.644 |     1666. |   -0.5333 |
#> |    U|     44833.531 |     3.631 |     83.31 |    0.4767 |
#> |  732|     44833.520 |    -7.644 |     1666. |   -0.5328 |
#> |    U|     44833.520 |     3.631 |     83.31 |    0.4772 |
#> |  733|     44833.520 |    -7.643 |     1666. |   -0.5328 |
#> |    U|     44833.520 |     3.631 |     83.31 |    0.4772 |
#> |  734|     44833.522 |    -7.643 |     1666. |   -0.5330 |
#> |    U|     44833.522 |     3.631 |     83.31 |    0.4770 |
#> |  735|     44833.520 |    -7.643 |     1666. |   -0.5328 |
#> |    U|     44833.520 |     3.631 |     83.31 |    0.4772 |
#> |  736|     44833.520 |    -7.643 |     1666. |   -0.5328 |
#> |    U|     44833.520 |     3.631 |     83.31 |    0.4772 |
#> |  737|     44833.522 |    -7.643 |     1666. |   -0.5330 |
#> |    U|     44833.522 |     3.631 |     83.31 |    0.4770 |
#> |  738|     44833.520 |    -7.643 |     1666. |   -0.5327 |
#> |    U|     44833.520 |     3.631 |     83.31 |    0.4773 |
#> |  739|     44833.519 |    -7.642 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  740|     44833.519 |    -7.642 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  741|     44833.519 |    -7.642 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  742|     44833.519 |    -7.642 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  743|     44833.526 |    -7.642 |     1666. |   -0.5322 |
#> |    U|     44833.526 |     3.632 |     83.31 |    0.4778 |
#> |  744|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  745|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  746|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  747|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  748|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  749|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  750|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  751|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  752|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  753|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  754|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  755|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  756|     44833.519 |    -7.641 |     1666. |   -0.5326 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4774 |
#> |  757|     44833.519 |    -7.641 |     1666. |   -0.5326 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4774 |
#> |  758|     44833.520 |    -7.641 |     1666. |   -0.5325 |
#> |    U|     44833.520 |     3.632 |     83.31 |    0.4775 |
#> |  759|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  760|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  761|     44833.520 |    -7.641 |     1666. |   -0.5328 |
#> |    U|     44833.520 |     3.632 |     83.31 |    0.4772 |
#> |  762|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  763|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  764|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  765|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  766|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  767|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  768|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  769|     44833.519 |    -7.642 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  770|     44833.519 |    -7.642 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  771|     44833.520 |    -7.642 |     1666. |   -0.5328 |
#> |    U|     44833.520 |     3.632 |     83.31 |    0.4772 |
#> |  772|     44833.519 |    -7.642 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  773|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  774|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  775|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  776|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  777|     44833.519 |    -7.642 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  778|     44833.519 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  779|     44833.519 |    -7.642 |     1666. |   -0.5327 |
#> |    U|     44833.519 |     3.632 |     83.31 |    0.4773 |
#> |  780|     44833.518 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.518 |     3.632 |     83.31 |    0.4773 |
#> |  781|     44833.518 |    -7.641 |     1666. |   -0.5327 |
#> |    U|     44833.518 |     3.632 |     83.31 |    0.4773 |
#> |  782|     44833.517 |    -7.641 |     1666. |   -0.5328 |
#> |    U|     44833.517 |     3.632 |     83.31 |    0.4772 |
#> |  783|     44833.514 |    -7.641 |     1667. |   -0.5329 |
#> |    U|     44833.514 |     3.632 |     83.31 |    0.4771 |
#> |  784|     44833.512 |    -7.640 |     1667. |   -0.5330 |
#> |    U|     44833.512 |     3.632 |     83.31 |    0.4770 |
#> |  785|     44833.511 |    -7.640 |     1667. |   -0.5332 |
#> |    U|     44833.511 |     3.632 |     83.32 |    0.4768 |
#> |  786|     44833.504 |    -7.640 |     1667. |   -0.5328 |
#> |    U|     44833.504 |     3.632 |     83.32 |    0.4772 |
#> |  787|     44833.499 |    -7.640 |     1667. |   -0.5327 |
#> |    U|     44833.499 |     3.632 |     83.32 |    0.4773 |
#> |  788|     44833.491 |    -7.638 |     1667. |   -0.5326 |
#> |    U|     44833.491 |     3.632 |     83.33 |    0.4774 |
#> |  789|     44833.474 |    -7.637 |     1668. |   -0.5326 |
#> |    U|     44833.474 |     3.633 |     83.34 |    0.4774 |
#> |  790|     44833.443 |    -7.632 |     1670. |   -0.5325 |
#> |    U|     44833.443 |     3.634 |     83.37 |    0.4775 |
#> |  791|     44833.388 |    -7.626 |     1673. |   -0.5323 |
#> |    U|     44833.388 |     3.635 |     83.43 |    0.4777 |
#> |  792|     44833.307 |    -7.611 |     1679. |   -0.5319 |
#> |    U|     44833.307 |     3.638 |     83.55 |    0.4781 |
#> |  793|     44833.257 |    -7.587 |     1688. |   -0.5314 |
#> |    U|     44833.257 |     3.643 |     83.74 |    0.4786 |
#> |  794|     44833.257 |    -7.586 |     1688. |   -0.5313 |
#> |    U|     44833.257 |     3.643 |     83.74 |    0.4787 |
#> |  795|     44935.692 |    -7.587 |     1688. |   -0.5840 |
#> |    U|     44935.692 |     3.643 |     83.74 |    0.4260 |
#> |  796|     44834.195 |    -7.546 |     1688. |   -0.5251 |
#> |    U|     44834.195 |     3.651 |     83.74 |    0.4849 |
#> |  797|     44834.857 |    -7.612 |     1688. |   -0.5247 |
#> |    U|     44834.857 |     3.638 |     83.74 |    0.4853 |
#> |  798|     44833.970 |    -7.576 |     1688. |   -0.5261 |
#> |    U|     44833.970 |     3.645 |     83.74 |    0.4839 |
#> |  799|     44837.149 |    -7.585 |     1688. |   -0.5197 |
#> |    U|     44837.149 |     3.643 |     83.74 |    0.4903 |
#> |  800|     44833.273 |    -7.593 |     1688. |   -0.5308 |
#> |    U|     44833.273 |     3.641 |     83.74 |    0.4792 |
#> |  801|     44834.139 |    -7.587 |     1688. |   -0.5366 |
#> |    U|     44834.139 |     3.643 |     83.74 |    0.4734 |
#> |  802|     44833.265 |    -7.584 |     1688. |   -0.5307 |
#> |    U|     44833.265 |     3.643 |     83.74 |    0.4793 |
#> |  803|     44833.257 |    -7.584 |     1688. |   -0.5312 |
#> |    U|     44833.257 |     3.643 |     83.74 |    0.4788 |
#> |  804|     44833.258 |    -7.584 |     1688. |   -0.5311 |
#> |    U|     44833.258 |     3.643 |     83.74 |    0.4789 |
#> |  805|     44833.261 |    -7.589 |     1688. |   -0.5309 |
#> |    U|     44833.261 |     3.642 |     83.74 |    0.4791 |
#> |  806|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  807|     44833.268 |    -7.587 |     1688. |   -0.5307 |
#> |    U|     44833.268 |     3.643 |     83.74 |    0.4793 |
#> |  808|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.642 |     83.74 |    0.4787 |
#> |  809|     44833.257 |    -7.588 |     1688. |   -0.5311 |
#> |    U|     44833.257 |     3.642 |     83.74 |    0.4789 |
#> |  810|     44833.257 |    -7.589 |     1688. |   -0.5314 |
#> |    U|     44833.257 |     3.642 |     83.74 |    0.4786 |
#> |  811|     44833.258 |    -7.588 |     1688. |   -0.5315 |
#> |    U|     44833.258 |     3.642 |     83.74 |    0.4785 |
#> |  812|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.642 |     83.74 |    0.4787 |
#> |  813|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.642 |     83.74 |    0.4787 |
#> |  814|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.642 |     83.74 |    0.4787 |
#> |  815|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.642 |     83.74 |    0.4787 |
#> |  816|     44833.256 |    -7.588 |     1688. |   -0.5314 |
#> |    U|     44833.256 |     3.642 |     83.74 |    0.4786 |
#> |  817|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.642 |     83.74 |    0.4787 |
#> |  818|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  819|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  820|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  821|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  822|     44833.256 |    -7.588 |     1688. |   -0.5314 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4786 |
#> |  823|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  824|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  825|     44833.256 |    -7.587 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  826|     44833.256 |    -7.588 |     1688. |   -0.5314 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4786 |
#> |  827|     44833.256 |    -7.587 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  828|     44833.256 |    -7.587 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  829|     44833.256 |    -7.587 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  830|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  831|     44833.256 |    -7.587 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  832|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  833|     44833.256 |    -7.587 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  834|     44833.256 |    -7.588 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  835|     44833.256 |    -7.587 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  836|     44833.256 |    -7.587 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  837|     44833.256 |    -7.587 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> |  838|     44833.256 |    -7.587 |     1688. |   -0.5313 |
#> |    U|     44833.256 |     3.643 |     83.74 |    0.4787 |
#> 
#> → creating full model...
#> → pruning branches (`if`/`else`)...
#>  done
#> → loading into symengine environment...
#>  done
#> → finding duplicate expressions in EBE model...
#> 
#> → optimizing duplicate expressions in EBE model...
#> 
#> → compiling EBE model...
#>  
#>  done
#> Calculating residuals/tables
#> done

if (inherits(fit, "nlmixrDynmodel")) {
 as.dynmodel(fit)
}
#>             est       %cv
#> CL    3.6425736 0.5784072
#> V    83.7426485 0.7269676
#> prop  0.4787147 1.0262525
#> 
#>  -loglik      AIC      BIC 
#> 44833.26 89672.51 89693.05 
#> 

# method = "focei" is slightly more flexible and well tested

fit <- try(nlmixr(object = model_onecmt_bolus, data = Bolus_1CPT, est = "focei"))
#>  parameter labels from comments will be replaced by 'label()'
#> Key: U: Unscaled Parameters; X: Back-transformed parameters; G: Gill difference gradient approximation
#> F: Forward difference gradient approximation
#> C: Central difference gradient approximation
#> M: Mixed forward and central difference gradient approximation
#> Unscaled parameters for Omegas=chol(solve(omega));
#> Diagonals are transformed, as specified by foceiControl(diagXform=)
#> |-----+---------------+-----------+-----------+-----------|
#> |    #| Objective Fun |        CL |         V |  prop.err |
#> |    1| 8.0454138e+09 |   -0.8004 |     1.000 |    -1.000 |
#> |    U| 8.0454138e+09 |     5.000 |     50.00 |   0.01000 |
#> |    X| 8.0454138e+09 |     5.000 |     50.00 |   0.01000 |
#> |    G|    Gill Diff. | 1.154e+11 |-9.901e+10 |-8.044e+09 |
#> |    2|     25787707. |    -1.558 |     1.650 |   -0.9472 |
#> |    U|      25787707 |     1.210 |     82.51 |   0.01026 |
#> |    X|      25787707 |     1.210 |     82.51 |   0.01026 |
#> |    M|   Mixed Diff. |-5.748e+07 | 1.415e+06 |-2.509e+07 |
#> |    3|     12967373. |    -1.286 |     1.943 |   -0.6466 |
#> |    U|      12967373 |     2.572 |     97.13 |   0.01177 |
#> |    X|      12967373 |     2.572 |     97.13 |   0.01177 |
#> |    M|   Mixed Diff. |-1.429e+07 | 7.740e+06 |-1.100e+07 |
#> |    4|     7423175.1 |    -1.178 |     1.725 |   -0.2093 |
#> |    U|     7423175.1 |     3.111 |     86.27 |   0.01395 |
#> |    X|     7423175.1 |     3.111 |     86.27 |   0.01395 |
#> |    M|   Mixed Diff. |-1.180e+06 | 4.378e+06 |-5.298e+06 |
#> |    5|     5484755.1 |    -1.144 |     1.430 |    0.1923 |
#> |    U|     5484755.1 |     3.281 |     71.48 |   0.01596 |
#> |    X|     5484755.1 |     3.281 |     71.48 |   0.01596 |
#> |    M|   Mixed Diff. | 1.408e+07 |-2.824e+06 |-3.417e+06 |
#> |    6|     6679839.8 |    -1.455 |     1.319 |    0.5677 |
#> |    U|     6679839.8 |     1.725 |     65.93 |   0.01784 |
#> |    X|     6679839.8 |     1.725 |     65.93 |   0.01784 |
#> |    7|     6134001.2 |    -1.339 |     1.469 |    0.2396 |
#> |    U|     6134001.2 |     2.306 |     73.43 |   0.01620 |
#> |    X|     6134001.2 |     2.306 |     73.43 |   0.01620 |
#> |    8|     5095675.6 |    -1.224 |     1.446 |    0.2118 |
#> |    U|     5095675.6 |     2.880 |     72.28 |   0.01606 |
#> |    X|     5095675.6 |     2.880 |     72.28 |   0.01606 |
#> |    M|   Mixed Diff. |-3.643e+06 | 1.099e+06 |-3.153e+06 |
#> |    9|     4822013.6 |    -1.201 |     1.411 |    0.2847 |
#> |    U|     4822013.6 |     2.998 |     70.55 |   0.01642 |
#> |    X|     4822013.6 |     2.998 |     70.55 |   0.01642 |
#> |   10|     4570036.5 |    -1.211 |     1.361 |    0.3767 |
#> |    U|     4570036.5 |     2.949 |     68.05 |   0.01688 |
#> |    X|     4570036.5 |     2.949 |     68.05 |   0.01688 |
#> |   11|     4136671.7 |    -1.235 |     1.236 |    0.6070 |
#> |    U|     4136671.7 |     2.828 |     61.81 |   0.01803 |
#> |    X|     4136671.7 |     2.828 |     61.81 |   0.01803 |
#> |    M|   Mixed Diff. | 1.884e+06 |-2.107e+06 |-2.274e+06 |
#> |   12|     5576495.6 |    -1.467 |     1.193 |    0.9869 |
#> |    U|     5576495.6 |     1.667 |     59.63 |   0.01993 |
#> |    X|     5576495.6 |     1.667 |     59.63 |   0.01993 |
#> |   13|     4152428.3 |    -1.288 |     1.295 |    0.6710 |
#> |    U|     4152428.3 |     2.563 |     64.77 |   0.01836 |
#> |    X|     4152428.3 |     2.563 |     64.77 |   0.01836 |
#> |   14|     4065196.4 |    -1.260 |     1.265 |    0.6377 |
#> |    U|     4065196.4 |     2.701 |     63.23 |   0.01819 |
#> |    X|     4065196.4 |     2.701 |     63.23 |   0.01819 |
#> |    M|   Mixed Diff. |-3.874e+06 |-4.982e+05 |-2.215e+06 |
#> |   15|     3971634.9 |    -1.234 |     1.246 |    0.6742 |
#> |    U|     3971634.9 |     2.834 |     62.28 |   0.01837 |
#> |    X|     3971634.9 |     2.834 |     62.28 |   0.01837 |
#> |    M|   Mixed Diff. | 1.547e+06 |-1.857e+06 |-2.143e+06 |
#> |   16|     3901114.6 |    -1.257 |     1.274 |    0.7067 |
#> |    U|     3901114.6 |     2.717 |     63.69 |   0.01853 |
#> |    X|     3901114.6 |     2.717 |     63.69 |   0.01853 |
#> |    M|   Mixed Diff. |-3.528e+06 |-4.371e+05 |-2.086e+06 |
#> |   17|     3814678.8 |    -1.231 |     1.255 |    0.7436 |
#> |    U|     3814678.8 |     2.847 |     62.75 |   0.01872 |
#> |    X|     3814678.8 |     2.847 |     62.75 |   0.01872 |
#> |    M|   Mixed Diff. | 1.560e+06 |-1.707e+06 |-2.019e+06 |
#> |   18|     3749677.4 |    -1.257 |     1.270 |    0.7824 |
#> |    U|     3749677.4 |     2.717 |     63.48 |   0.01891 |
#> |    X|     3749677.4 |     2.717 |     63.48 |   0.01891 |
#> |    M|   Mixed Diff. |-3.280e+06 |-4.752e+05 |-1.964e+06 |
#> |   19|     3672806.1 |    -1.232 |     1.249 |    0.8196 |
#> |    U|     3672806.1 |     2.839 |     62.46 |   0.01910 |
#> |    X|     3672806.1 |     2.839 |     62.46 |   0.01910 |
#> |    M|   Mixed Diff. | 1.459e+06 |-1.688e+06 |-1.905e+06 |
#> |   20|     3612164.8 |    -1.259 |     1.262 |    0.8590 |
#> |    U|     3612164.8 |     2.709 |     63.12 |   0.01929 |
#> |    X|     3612164.8 |     2.709 |     63.12 |   0.01929 |
#> |    M|   Mixed Diff. |-3.182e+06 |-5.098e+05 |-1.853e+06 |
#> |   21|     3542845.8 |    -1.235 |     1.241 |    0.8959 |
#> |    U|     3542845.8 |     2.828 |     62.03 |   0.01948 |
#> |    X|     3542845.8 |     2.828 |     62.03 |   0.01948 |
#> |    M|   Mixed Diff. | 1.380e+06 |-1.702e+06 |-1.800e+06 |
#> |   22|     3485723.4 |    -1.253 |     1.282 |    0.9147 |
#> |    U|     3485723.4 |     2.737 |     64.11 |   0.01957 |
#> |    X|     3485723.4 |     2.737 |     64.11 |   0.01957 |
#> |    M|   Mixed Diff. |-2.843e+06 |-3.847e+05 |-1.762e+06 |
#> |   23|     3417853.0 |    -1.228 |     1.263 |    0.9523 |
#> |    U|       3417853 |     2.861 |     63.15 |   0.01976 |
#> |    X|       3417853 |     2.861 |     63.15 |   0.01976 |
#> |    M|   Mixed Diff. | 1.533e+06 |-1.488e+06 |-1.711e+06 |
#> |   24|     3366264.9 |    -1.255 |     1.264 |    0.9931 |
#> |    U|     3366264.9 |     2.725 |     63.18 |   0.01997 |
#> |    X|     3366264.9 |     2.725 |     63.18 |   0.01997 |
#> |    M|   Mixed Diff. |-2.591e+06 |-5.389e+05 |-1.668e+06 |
#> |   25|     3310951.5 |    -1.233 |     1.242 |     1.031 |
#> |    U|     3310951.5 |     2.835 |     62.11 |   0.02016 |
#> |    X|     3310951.5 |     2.835 |     62.11 |   0.02016 |
#> |    M|   Mixed Diff. | 1.471e+06 |-1.622e+06 |-1.625e+06 |
#> |   26|     3262970.5 |    -1.248 |     1.288 |     1.038 |
#> |    U|     3262970.5 |     2.762 |     64.42 |   0.02019 |
#> |    X|     3262970.5 |     2.762 |     64.42 |   0.02019 |
#> |    M|   Mixed Diff. |-2.205e+06 |-4.018e+05 |-1.598e+06 |
#> |   27|     3207143.4 |    -1.224 |     1.272 |     1.078 |
#> |    U|     3207143.4 |     2.884 |     63.62 |   0.02039 |
#> |    X|     3207143.4 |     2.884 |     63.62 |   0.02039 |
#> |    M|   Mixed Diff. | 1.799e+06 |-1.405e+06 |-1.555e+06 |
#> |   28|     3160019.1 |    -1.251 |     1.264 |     1.117 |
#> |    U|     3160019.1 |     2.745 |     63.19 |   0.02059 |
#> |    X|     3160019.1 |     2.745 |     63.19 |   0.02059 |
#> |    M|   Mixed Diff. |-1.961e+06 |-6.010e+05 |-1.517e+06 |
#> |   29|     3114181.2 |    -1.230 |     1.246 |     1.158 |
#> |    U|     3114181.2 |     2.851 |     62.30 |   0.02079 |
#> |    X|     3114181.2 |     2.851 |     62.30 |   0.02079 |
#> |    M|   Mixed Diff. | 1.757e+06 |-1.589e+06 |-1.480e+06 |
#> |   30|     3072951.8 |    -1.243 |     1.293 |     1.155 |
#> |    U|     3072951.8 |     2.788 |     64.66 |   0.02077 |
#> |    X|     3072951.8 |     2.788 |     64.66 |   0.02077 |
#> |    M|   Mixed Diff. |-1.580e+06 |-4.422e+05 |-1.461e+06 |
#> |   31|     3026941.9 |    -1.216 |     1.288 |     1.196 |
#> |    U|     3026941.9 |     2.923 |     64.38 |   0.02098 |
#> |    X|     3026941.9 |     2.923 |     64.38 |   0.02098 |
#> |    M|   Mixed Diff. | 2.326e+06 |-1.356e+06 |-1.426e+06 |
#> |   32|     2974775.5 |    -1.245 |     1.274 |     1.233 |
#> |    U|     2974775.5 |     2.779 |     63.71 |   0.02116 |
#> |    X|     2974775.5 |     2.779 |     63.71 |   0.02116 |
#> |    M|   Mixed Diff. |-1.293e+06 |-6.083e+05 |-1.388e+06 |
#> |   33|     2928328.1 |    -1.220 |     1.272 |     1.275 |
#> |    U|     2928328.1 |     2.901 |     63.59 |   0.02138 |
#> |    X|     2928328.1 |     2.901 |     63.59 |   0.02138 |
#> |    M|   Mixed Diff. | 2.182e+06 |-1.421e+06 |-1.353e+06 |
#> |   34|     2885488.9 |    -1.249 |     1.256 |     1.312 |
#> |    U|     2885488.9 |     2.758 |     62.80 |   0.02156 |
#> |    X|     2885488.9 |     2.758 |     62.80 |   0.02156 |
#> |    M|   Mixed Diff. |-1.287e+06 |-7.076e+05 |-1.321e+06 |
#> |   35|     2841408.7 |    -1.224 |     1.255 |     1.354 |
#> |    U|     2841408.7 |     2.883 |     62.76 |   0.02177 |
#> |    X|     2841408.7 |     2.883 |     62.76 |   0.02177 |
#> |    M|   Mixed Diff. | 2.222e+06 |-1.535e+06 |-1.288e+06 |
#> |   36|     2802790.3 |    -1.237 |     1.302 |     1.345 |
#> |    U|     2802790.3 |     2.814 |     65.08 |   0.02173 |
#> |    X|     2802790.3 |     2.814 |     65.08 |   0.02173 |
#> |    M|   Mixed Diff. |-1.051e+06 |-4.270e+05 |-1.273e+06 |
#> |   37|     2766566.6 |    -1.207 |     1.314 |     1.382 |
#> |    U|     2766566.6 |     2.965 |     65.69 |   0.02191 |
#> |    X|     2766566.6 |     2.965 |     65.69 |   0.02191 |
#> |    M|   Mixed Diff. | 2.416e+06 |-1.112e+06 |-1.246e+06 |
#> |   38|     2711392.0 |    -1.236 |     1.299 |     1.419 |
#> |    U|       2711392 |     2.821 |     64.97 |   0.02209 |
#> |    X|       2711392 |     2.821 |     64.97 |   0.02209 |
#> |    M|   Mixed Diff. |-8.259e+05 |-4.658e+05 |-1.210e+06 |
#> |   39|     2669008.7 |    -1.210 |     1.314 |     1.457 |
#> |    U|     2669008.7 |     2.953 |     65.71 |   0.02229 |
#> |    X|     2669008.7 |     2.953 |     65.71 |   0.02229 |
#> |    M|   Mixed Diff. | 1.969e+06 |-9.814e+05 |-1.181e+06 |
#> |   40|     2621945.7 |    -1.237 |     1.299 |     1.495 |
#> |    U|     2621945.7 |     2.818 |     64.95 |   0.02248 |
#> |    X|     2621945.7 |     2.818 |     64.95 |   0.02248 |
#> |    M|   Mixed Diff. |-8.597e+05 |-4.406e+05 |-1.150e+06 |
#> |   41|     2584087.7 |    -1.210 |     1.310 |     1.534 |
#> |    U|     2584087.7 |     2.953 |     65.52 |   0.02267 |
#> |    X|     2584087.7 |     2.953 |     65.52 |   0.02267 |
#> |    M|   Mixed Diff. | 2.032e+06 |-1.007e+06 |-1.123e+06 |
#> |   42|     2539660.8 |    -1.237 |     1.294 |     1.571 |
#> |    U|     2539660.8 |     2.815 |     64.68 |   0.02286 |
#> |    X|     2539660.8 |     2.815 |     64.68 |   0.02286 |
#> |    M|   Mixed Diff. |-7.816e+05 |-4.693e+05 |-1.094e+06 |
#> |   43|     2501720.2 |    -1.211 |     1.310 |     1.609 |
#> |    U|     2501720.2 |     2.949 |     65.49 |   0.02304 |
#> |    X|     2501720.2 |     2.949 |     65.49 |   0.02304 |
#> |    M|   Mixed Diff. | 1.890e+06 |-9.606e+05 |-1.069e+06 |
#> |   44|     2461300.1 |    -1.238 |     1.292 |     1.645 |
#> |    U|     2461300.1 |     2.813 |     64.60 |   0.02323 |
#> |    X|     2461300.1 |     2.813 |     64.60 |   0.02323 |
#> |    M|   Mixed Diff. |-7.607e+05 |-4.634e+05 |-1.043e+06 |
#> |   45|     2425532.7 |    -1.211 |     1.309 |     1.683 |
#> |    U|     2425532.7 |     2.949 |     65.43 |   0.02341 |
#> |    X|     2425532.7 |     2.949 |     65.43 |   0.02341 |
#> |    M|   Mixed Diff. | 1.857e+06 |-9.451e+05 |-1.020e+06 |
#> |   46|     2387773.7 |    -1.238 |     1.290 |     1.719 |
#> |    U|     2387773.7 |     2.812 |     64.49 |   0.02359 |
#> |    X|     2387773.7 |     2.812 |     64.49 |   0.02359 |
#> |    M|   Mixed Diff. |-7.144e+05 |-4.668e+05 |-9.957e+05 |
#> |   47|     2352515.6 |    -1.211 |     1.307 |     1.756 |
#> |    U|     2352515.6 |     2.945 |     65.37 |   0.02378 |
#> |    X|     2352515.6 |     2.945 |     65.37 |   0.02378 |
#> |    M|   Mixed Diff. | 1.754e+06 |-9.135e+05 |-9.733e+05 |
#> |   48|     2318063.0 |    -1.238 |     1.288 |     1.792 |
#> |    U|       2318063 |     2.810 |     64.39 |   0.02396 |
#> |    X|       2318063 |     2.810 |     64.39 |   0.02396 |
#> |    M|   Mixed Diff. |-6.926e+05 |-4.652e+05 |-9.513e+05 |
#> |   49|     2284308.2 |    -1.212 |     1.306 |     1.829 |
#> |    U|     2284308.2 |     2.944 |     65.29 |   0.02414 |
#> |    X|     2284308.2 |     2.944 |     65.29 |   0.02414 |
#> |    M|   Mixed Diff. | 1.710e+06 |-8.983e+05 |-9.303e+05 |
#> |   50|     2252408.3 |    -1.239 |     1.285 |     1.864 |
#> |    U|     2252408.3 |     2.808 |     64.26 |   0.02432 |
#> |    X|     2252408.3 |     2.808 |     64.26 |   0.02432 |
#> |    M|   Mixed Diff. |-6.606e+05 |-4.677e+05 |-9.101e+05 |
#> |   51|     2219352.7 |    -1.212 |     1.304 |     1.900 |
#> |    U|     2219352.7 |     2.941 |     65.20 |   0.02450 |
#> |    X|     2219352.7 |     2.941 |     65.20 |   0.02450 |
#> |    M|   Mixed Diff. | 1.634e+06 |-8.762e+05 |-8.901e+05 |
#> |   52|     2190158.1 |    -1.239 |     1.283 |     1.935 |
#> |    U|     2190158.1 |     2.805 |     64.15 |   0.02468 |
#> |    X|     2190158.1 |     2.805 |     64.15 |   0.02468 |
#> |    M|   Mixed Diff. |-6.416e+05 |-4.673e+05 |-8.716e+05 |
#> |   53|     2158284.4 |    -1.213 |     1.302 |     1.972 |
#> |    U|     2158284.4 |     2.939 |     65.12 |   0.02486 |
#> |    X|     2158284.4 |     2.939 |     65.12 |   0.02486 |
#> |    M|   Mixed Diff. | 1.591e+06 |-8.627e+05 |-8.527e+05 |
#> |   54|     2130976.5 |    -1.240 |     1.281 |     2.006 |
#> |    U|     2130976.5 |     2.803 |     64.03 |   0.02503 |
#> |    X|     2130976.5 |     2.803 |     64.03 |   0.02503 |
#> |    M|   Mixed Diff. |-6.159e+05 |-4.678e+05 |-8.356e+05 |
#> |   55|     2099817.5 |    -1.213 |     1.301 |     2.042 |
#> |    U|     2099817.5 |     2.936 |     65.04 |   0.02521 |
#> |    X|     2099817.5 |     2.936 |     65.04 |   0.02521 |
#> |    M|   Mixed Diff. | 1.529e+06 |-8.434e+05 |-8.175e+05 |
#> |   56|     2083775.9 |    -1.228 |     1.346 |     2.031 |
#> |    U|     2083775.9 |     2.862 |     67.31 |   0.02516 |
#> |    X|     2083775.9 |     2.862 |     67.31 |   0.02516 |
#> |    M|   Mixed Diff. |-7.174e+05 |-1.120e+05 |-8.127e+05 |
#> |   57|     2056866.5 |    -1.211 |     1.329 |     2.074 |
#> |    U|     2056866.5 |     2.946 |     66.46 |   0.02537 |
#> |    X|     2056866.5 |     2.946 |     66.46 |   0.02537 |
#> |    M|   Mixed Diff. | 1.023e+06 |-5.581e+05 |-7.954e+05 |
#> |   58|     2032568.0 |    -1.237 |     1.311 |     2.112 |
#> |    U|       2032568 |     2.819 |     65.56 |   0.02556 |
#> |    X|       2032568 |     2.819 |     65.56 |   0.02556 |
#> |    M|   Mixed Diff. |-8.471e+05 |-2.455e+05 |-7.797e+05 |
#> |   59|     2013116.7 |    -1.220 |     1.290 |     2.152 |
#> |    U|     2013116.7 |     2.904 |     64.48 |   0.02576 |
#> |    X|     2013116.7 |     2.904 |     64.48 |   0.02576 |
#> |    M|   Mixed Diff. | 1.087e+06 |-7.766e+05 |-7.661e+05 |
#> |   60|     1994230.6 |    -1.227 |     1.338 |     2.146 |
#> |    U|     1994230.6 |     2.865 |     66.88 |   0.02573 |
#> |    X|     1994230.6 |     2.865 |     66.88 |   0.02573 |
#> |    M|   Mixed Diff. |-5.271e+05 |-1.771e+05 |-7.596e+05 |
#> |   61|     1975457.1 |    -1.200 |     1.347 |     2.186 |
#> |    U|     1975457.1 |     3.002 |     67.34 |   0.02593 |
#> |    X|     1975457.1 |     3.002 |     67.34 |   0.02593 |
#> |    M|   Mixed Diff. | 1.643e+06 |-5.962e+05 |-7.468e+05 |
#> |   62|     1939273.5 |    -1.227 |     1.329 |     2.222 |
#> |    U|     1939273.5 |     2.866 |     66.45 |   0.02611 |
#> |    X|     1939273.5 |     2.866 |     66.45 |   0.02611 |
#> |    M|   Mixed Diff. |-3.598e+05 |-2.423e+05 |-7.274e+05 |
#> |   63|     1911533.5 |    -1.206 |     1.343 |     2.265 |
#> |    U|     1911533.5 |     2.970 |     67.15 |   0.02632 |
#> |    X|     1911533.5 |     2.970 |     67.15 |   0.02632 |
#> |    M|   Mixed Diff. | 1.105e+06 |-4.844e+05 |-7.112e+05 |
#> |   64|     1884094.4 |    -1.229 |     1.323 |     2.303 |
#> |    U|     1884094.4 |     2.855 |     66.17 |   0.02652 |
#> |    X|     1884094.4 |     2.855 |     66.17 |   0.02652 |
#> |    M|   Mixed Diff. |-4.316e+05 |-2.435e+05 |-6.955e+05 |
#> |   65|     1861890.8 |    -1.205 |     1.337 |     2.343 |
#> |    U|     1861890.8 |     2.979 |     66.87 |   0.02672 |
#> |    X|     1861890.8 |     2.979 |     66.87 |   0.02672 |
#> |    M|   Mixed Diff. | 1.338e+06 |-5.595e+05 |-6.821e+05 |
#> |   66|     1834720.9 |    -1.230 |     1.316 |     2.379 |
#> |    U|     1834720.9 |     2.851 |     65.80 |   0.02689 |
#> |    X|     1834720.9 |     2.851 |     65.80 |   0.02689 |
#> |    M|   Mixed Diff. |-3.665e+05 |-2.806e+05 |-6.672e+05 |
#> |   67|     1809312.3 |    -1.208 |     1.333 |     2.419 |
#> |    U|     1809312.3 |     2.962 |     66.65 |   0.02710 |
#> |    X|     1809312.3 |     2.962 |     66.65 |   0.02710 |
#> |    M|   Mixed Diff. | 1.097e+06 |-5.180e+05 |-6.530e+05 |
#> |   68|     1786978.9 |    -1.232 |     1.310 |     2.456 |
#> |    U|     1786978.9 |     2.842 |     65.52 |   0.02728 |
#> |    X|     1786978.9 |     2.842 |     65.52 |   0.02728 |
#> |    M|   Mixed Diff. |-4.071e+05 |-2.870e+05 |-6.403e+05 |
#> |   69|     1764860.1 |    -1.207 |     1.328 |     2.494 |
#> |    U|     1764860.1 |     2.965 |     66.39 |   0.02747 |
#> |    X|     1764860.1 |     2.965 |     66.39 |   0.02747 |
#> |    M|   Mixed Diff. | 1.222e+06 |-5.653e+05 |-6.279e+05 |
#> |   70|     1743736.5 |    -1.233 |     1.304 |     2.528 |
#> |    U|     1743736.5 |     2.837 |     65.18 |   0.02764 |
#> |    X|     1743736.5 |     2.837 |     65.18 |   0.02764 |
#> |    M|   Mixed Diff. |-3.681e+05 |-3.146e+05 |-6.161e+05 |
#> |   71|     1719724.5 |    -1.210 |     1.323 |     2.567 |
#> |    U|     1719724.5 |     2.952 |     66.16 |   0.02783 |
#> |    X|     1719724.5 |     2.952 |     66.16 |   0.02783 |
#> |    M|   Mixed Diff. | 1.065e+06 |-5.417e+05 |-6.034e+05 |
#> |   72|     1701725.7 |    -1.235 |     1.299 |     2.601 |
#> |    U|     1701725.7 |     2.829 |     64.94 |   0.02801 |
#> |    X|     1701725.7 |     2.829 |     64.94 |   0.02801 |
#> |    M|   Mixed Diff. |-3.987e+05 |-3.185e+05 |-5.930e+05 |
#> |   73|     1680253.3 |    -1.210 |     1.319 |     2.638 |
#> |    U|     1680253.3 |     2.954 |     65.93 |   0.02819 |
#> |    X|     1680253.3 |     2.954 |     65.93 |   0.02819 |
#> |    M|   Mixed Diff. | 1.158e+06 |-5.775e+05 |-5.817e+05 |
#> |   74|     1669477.0 |    -1.223 |     1.365 |     2.628 |
#> |    U|       1669477 |     2.886 |     68.23 |   0.02814 |
#> |    X|       1669477 |     2.886 |     68.23 |   0.02814 |
#> |    M|   Mixed Diff. |-4.940e+05 |-3.432e+04 |-5.788e+05 |
#> |   75|     1650682.8 |    -1.210 |     1.342 |     2.670 |
#> |    U|     1650682.8 |     2.951 |     67.11 |   0.02835 |
#> |    X|     1650682.8 |     2.951 |     67.11 |   0.02835 |
#> |    M|   Mixed Diff. | 6.726e+05 |-3.584e+05 |-5.680e+05 |
#> |   76|     1636142.9 |    -1.235 |     1.322 |     2.707 |
#> |    U|     1636142.9 |     2.826 |     66.09 |   0.02853 |
#> |    X|     1636142.9 |     2.826 |     66.09 |   0.02853 |
#> |    M|   Mixed Diff. |-7.259e+05 |-1.485e+05 |-5.590e+05 |
#> |   77|     1625691.3 |    -1.220 |     1.293 |     2.743 |
#> |    U|     1625691.3 |     2.900 |     64.63 |   0.02872 |
#> |    X|     1625691.3 |     2.900 |     64.63 |   0.02872 |
#> |    M|   Mixed Diff. | 7.482e+05 |-5.822e+05 |-5.519e+05 |
#> |   78|     1610071.0 |    -1.226 |     1.341 |     2.740 |
#> |    U|       1610071 |     2.869 |     67.06 |   0.02870 |
#> |    X|       1610071 |     2.869 |     67.06 |   0.02870 |
#> |    M|   Mixed Diff. |-4.127e+05 |-1.320e+05 |-5.467e+05 |
#> |   79|     1600512.6 |    -1.198 |     1.350 |     2.778 |
#> |    U|     1600512.6 |     3.014 |     67.52 |   0.02889 |
#> |    X|     1600512.6 |     3.014 |     67.52 |   0.02889 |
#> |    M|   Mixed Diff. | 1.445e+06 |-4.948e+05 |-5.400e+05 |
#> |   80|     1572890.9 |    -1.226 |     1.330 |     2.813 |
#> |    U|     1572890.9 |     2.872 |     66.49 |   0.02906 |
#> |    X|     1572890.9 |     2.872 |     66.49 |   0.02906 |
#> |    M|   Mixed Diff. |-2.273e+05 |-2.064e+05 |-5.270e+05 |
#> |   81|     1550921.4 |    -1.208 |     1.346 |     2.855 |
#> |    U|     1550921.4 |     2.964 |     67.32 |   0.02927 |
#> |    X|     1550921.4 |     2.964 |     67.32 |   0.02927 |
#> |    M|   Mixed Diff. | 7.425e+05 |-3.452e+05 |-5.158e+05 |
#> |   82|     1532851.4 |    -1.229 |     1.325 |     2.893 |
#> |    U|     1532851.4 |     2.859 |     66.24 |   0.02947 |
#> |    X|     1532851.4 |     2.859 |     66.24 |   0.02947 |
#> |    M|   Mixed Diff. |-3.292e+05 |-1.976e+05 |-5.061e+05 |
#> |   83|     1517297.7 |    -1.205 |     1.333 |     2.936 |
#> |    U|     1517297.7 |     2.975 |     66.66 |   0.02968 |
#> |    X|     1517297.7 |     2.975 |     66.66 |   0.02968 |
#> |    M|   Mixed Diff. | 1.090e+06 |-4.729e+05 |-4.974e+05 |
#> |   84|     1499081.5 |    -1.231 |     1.309 |     2.970 |
#> |    U|     1499081.5 |     2.848 |     65.45 |   0.02985 |
#> |    X|     1499081.5 |     2.848 |     65.45 |   0.02985 |
#> |    M|   Mixed Diff. |-2.573e+05 |-2.627e+05 |-4.882e+05 |
#> |   85|     1478476.3 |    -1.210 |     1.330 |     3.009 |
#> |    U|     1478476.3 |     2.951 |     66.50 |   0.03005 |
#> |    X|     1478476.3 |     2.951 |     66.50 |   0.03005 |
#> |    M|   Mixed Diff. | 7.811e+05 |-4.078e+05 |-4.783e+05 |
#> |   86|     1462590.4 |    -1.232 |     1.309 |     3.047 |
#> |    U|     1462590.4 |     2.841 |     65.43 |   0.03024 |
#> |    X|     1462590.4 |     2.841 |     65.43 |   0.03024 |
#> |    M|   Mixed Diff. |-3.293e+05 |-2.414e+05 |-4.698e+05 |
#> |   87|     1447186.4 |    -1.209 |     1.318 |     3.089 |
#> |    U|     1447186.4 |     2.957 |     65.92 |   0.03045 |
#> |    X|     1447186.4 |     2.957 |     65.92 |   0.03045 |
#> |    M|   Mixed Diff. | 1.031e+06 |-5.064e+05 |-4.617e+05 |
#> |   88|     1433743.2 |    -1.220 |     1.366 |     3.083 |
#> |    U|     1433743.2 |     2.903 |     68.29 |   0.03042 |
#> |    X|     1433743.2 |     2.903 |     68.29 |   0.03042 |
#> |    M|   Mixed Diff. |-2.603e+05 |-5.606e+04 |-4.576e+05 |
#> |   89|     1423051.7 |    -1.196 |     1.371 |     3.126 |
#> |    U|     1423051.7 |     3.023 |     68.55 |   0.03063 |
#> |    X|     1423051.7 |     3.023 |     68.55 |   0.03063 |
#> |    M|   Mixed Diff. | 1.084e+06 |-3.163e+05 |-4.511e+05 |
#> |   90|     1399910.0 |    -1.221 |     1.351 |     3.162 |
#> |    U|       1399910 |     2.896 |     67.54 |   0.03081 |
#> |    X|       1399910 |     2.896 |     67.54 |   0.03081 |
#> |    M|   Mixed Diff. |-1.789e+05 |-1.183e+05 |-4.407e+05 |
#> |   91|     1383049.1 |    -1.203 |     1.363 |     3.206 |
#> |    U|     1383049.1 |     2.985 |     68.13 |   0.03103 |
#> |    X|     1383049.1 |     2.985 |     68.13 |   0.03103 |
#> |    M|   Mixed Diff. | 6.988e+05 |-2.584e+05 |-4.323e+05 |
#> |   92|     1366345.6 |    -1.224 |     1.340 |     3.245 |
#> |    U|     1366345.6 |     2.881 |     67.00 |   0.03122 |
#> |    X|     1366345.6 |     2.881 |     67.00 |   0.03122 |
#> |    M|   Mixed Diff. |-2.202e+05 |-1.411e+05 |-4.241e+05 |
#> |   93|     1352268.4 |    -1.203 |     1.354 |     3.286 |
#> |    U|     1352268.4 |     2.989 |     67.70 |   0.03143 |
#> |    X|     1352268.4 |     2.989 |     67.70 |   0.03143 |
#> |    M|   Mixed Diff. | 8.461e+05 |-3.191e+05 |-4.169e+05 |
#> |   94|     1336060.9 |    -1.226 |     1.330 |     3.322 |
#> |    U|     1336060.9 |     2.873 |     66.48 |   0.03161 |
#> |    X|     1336060.9 |     2.873 |     66.48 |   0.03161 |
#> |    M|   Mixed Diff. |-1.854e+05 |-1.769e+05 |-4.093e+05 |
#> |   95|     1319364.8 |    -1.207 |     1.348 |     3.363 |
#> |    U|     1319364.8 |     2.967 |     67.38 |   0.03182 |
#> |    X|     1319364.8 |     2.967 |     67.38 |   0.03182 |
#> |    M|   Mixed Diff. | 6.515e+05 |-2.938e+05 |-4.015e+05 |
#> |   96|     1305198.4 |    -1.228 |     1.325 |     3.402 |
#> |    U|     1305198.4 |     2.864 |     66.25 |   0.03201 |
#> |    X|     1305198.4 |     2.864 |     66.25 |   0.03201 |
#> |    M|   Mixed Diff. |-2.312e+05 |-1.768e+05 |-3.944e+05 |
#> |   97|     1292054.7 |    -1.204 |     1.343 |     3.441 |
#> |    U|     1292054.7 |     2.979 |     67.14 |   0.03221 |
#> |    X|     1292054.7 |     2.979 |     67.14 |   0.03221 |
#> |    M|   Mixed Diff. | 8.423e+05 |-3.503e+05 |-3.881e+05 |
#> |   98|     1267756.8 |    -1.221 |     1.349 |     3.487 |
#> |    U|     1267756.8 |     2.895 |     67.45 |   0.03243 |
#> |    X|     1267756.8 |     2.895 |     67.45 |   0.03243 |
#> |    M|   Mixed Diff. |-1.565e+05 |-1.135e+05 |-3.777e+05 |
#> |   99|     1253412.8 |    -1.203 |     1.362 |     3.530 |
#> |    U|     1253412.8 |     2.985 |     68.10 |   0.03265 |
#> |    X|     1253412.8 |     2.985 |     68.10 |   0.03265 |
#> |    M|   Mixed Diff. | 6.343e+05 |-2.361e+05 |-3.709e+05 |
#> |  100|     1238692.5 |    -1.224 |     1.340 |     3.569 |
#> |    U|     1238692.5 |     2.883 |     67.01 |   0.03285 |
#> |    X|     1238692.5 |     2.883 |     67.01 |   0.03285 |
#> |    M|   Mixed Diff. |-1.842e+05 |-1.304e+05 |-3.641e+05 |
#> |  101|     1226329.8 |    -1.203 |     1.355 |     3.611 |
#> |    U|     1226329.8 |     2.988 |     67.76 |   0.03305 |
#> |    X|     1226329.8 |     2.988 |     67.76 |   0.03305 |
#> |    M|   Mixed Diff. | 7.365e+05 |-2.788e+05 |-3.582e+05 |
#> |  102|     1211817.4 |    -1.225 |     1.332 |     3.648 |
#> |    U|     1211817.4 |     2.877 |     66.61 |   0.03324 |
#> |    X|     1211817.4 |     2.877 |     66.61 |   0.03324 |
#> |    M|   Mixed Diff. |-1.582e+05 |-1.549e+05 |-3.516e+05 |
#> |  103|     1197573.1 |    -1.206 |     1.350 |     3.689 |
#> |    U|     1197573.1 |     2.970 |     67.52 |   0.03345 |
#> |    X|     1197573.1 |     2.970 |     67.52 |   0.03345 |
#> |    M|   Mixed Diff. | 5.849e+05 |-2.565e+05 |-3.453e+05 |
#> |  104|     1184554.1 |    -1.226 |     1.329 |     3.729 |
#> |    U|     1184554.1 |     2.870 |     66.47 |   0.03364 |
#> |    X|     1184554.1 |     2.870 |     66.47 |   0.03364 |
#> |    M|   Mixed Diff. |-1.950e+05 |-1.510e+05 |-3.392e+05 |
#> |  105|     1173493.1 |    -1.204 |     1.347 |     3.768 |
#> |    U|     1173493.1 |     2.984 |     67.35 |   0.03384 |
#> |    X|     1173493.1 |     2.984 |     67.35 |   0.03384 |
#> |    M|   Mixed Diff. | 7.555e+05 |-3.027e+05 |-3.341e+05 |
#> |  106|     1156493.1 |    -1.224 |     1.333 |     3.810 |
#> |    U|     1156493.1 |     2.880 |     66.65 |   0.03405 |
#> |    X|     1156493.1 |     2.880 |     66.65 |   0.03405 |
#> |    M|   Mixed Diff. |-1.372e+05 |-1.481e+05 |-3.269e+05 |
#> |  107|     1142654.1 |    -1.207 |     1.352 |     3.852 |
#> |    U|     1142654.1 |     2.967 |     67.60 |   0.03426 |
#> |    X|     1142654.1 |     2.967 |     67.60 |   0.03426 |
#> |    M|   Mixed Diff. | 5.065e+05 |-2.290e+05 |-3.209e+05 |
#> |  108|     1130678.3 |    -1.226 |     1.332 |     3.892 |
#> |    U|     1130678.3 |     2.871 |     66.59 |   0.03446 |
#> |    X|     1130678.3 |     2.871 |     66.59 |   0.03446 |
#> |    M|   Mixed Diff. |-2.007e+05 |-1.350e+05 |-3.154e+05 |
#> |  109|     1120765.4 |    -1.206 |     1.337 |     3.937 |
#> |    U|     1120765.4 |     2.973 |     66.87 |   0.03468 |
#> |    X|     1120765.4 |     2.973 |     66.87 |   0.03468 |
#> |    M|   Mixed Diff. | 7.246e+05 |-3.182e+05 |-3.107e+05 |
#> |  110|     1101136.9 |    -1.222 |     1.340 |     3.983 |
#> |    U|     1101136.9 |     2.890 |     67.00 |   0.03491 |
#> |    X|     1101136.9 |     2.890 |     67.00 |   0.03491 |
#> |    M|   Mixed Diff. |-1.006e+05 |-1.288e+05 |-3.029e+05 |
#> |  111|     1087324.2 |    -1.208 |     1.358 |     4.026 |
#> |    U|     1087324.2 |     2.962 |     67.92 |   0.03513 |
#> |    X|     1087324.2 |     2.962 |     67.92 |   0.03513 |
#> |  112|     1077650.9 |    -1.183 |     1.391 |     4.102 |
#> |    U|     1077650.9 |     3.088 |     69.54 |   0.03551 |
#> |    X|     1077650.9 |     3.088 |     69.54 |   0.03551 |
#> |    M|   Mixed Diff. | 1.216e+06 |-2.762e+05 |-2.914e+05 |
#> |  113|     1038151.0 |    -1.221 |     1.321 |     4.212 |
#> |    U|       1038151 |     2.898 |     66.07 |   0.03606 |
#> |    X|       1038151 |     2.898 |     66.07 |   0.03606 |
#> |    M|   Mixed Diff. | 1.406e+05 |-2.177e+05 |-2.757e+05 |
#> |  114|     1012702.9 |    -1.247 |     1.311 |     4.344 |
#> |    U|     1012702.9 |     2.769 |     65.53 |   0.03672 |
#> |    X|     1012702.9 |     2.769 |     65.53 |   0.03672 |
#> |    M|   Mixed Diff. |-7.818e+05 |-5.402e+04 |-2.635e+05 |
#> |  115|     990569.32 |    -1.234 |     1.251 |     4.466 |
#> |    U|     990569.32 |     2.832 |     62.56 |   0.03733 |
#> |    X|     990569.32 |     2.832 |     62.56 |   0.03733 |
#> |    M|   Mixed Diff. | 2.701e+05 |-4.133e+05 |-2.533e+05 |
#> |  116|     963948.95 |    -1.256 |     1.245 |     4.599 |
#> |    U|     963948.95 |     2.721 |     62.23 |   0.03800 |
#> |    X|     963948.95 |     2.721 |     62.23 |   0.03800 |
#> |    M|   Mixed Diff. |-6.203e+05 |-2.139e+05 |-2.417e+05 |
#> |  117|     928666.59 |    -1.213 |     1.371 |     4.620 |
#> |    U|     928666.59 |     2.935 |     68.57 |   0.03810 |
#> |    X|     928666.59 |     2.935 |     68.57 |   0.03810 |
#> |    M|   Mixed Diff. |     7378. |-5.822e+04 |-2.320e+05 |
#> |  118|     899875.97 |    -1.218 |     1.404 |     4.752 |
#> |    U|     899875.97 |     2.914 |     70.22 |   0.03876 |
#> |    X|     899875.97 |     2.914 |     70.22 |   0.03876 |
#> |  119|     844094.35 |    -1.230 |     1.503 |     5.146 |
#> |    U|     844094.35 |     2.851 |     75.17 |   0.04073 |
#> |    X|     844094.35 |     2.851 |     75.17 |   0.04073 |
#> |    M|   Mixed Diff. |-8.093e+05 | 2.736e+05 |-1.960e+05 |
#> |  120|     728576.65 |    -1.198 |     1.469 |     5.686 |
#> |    U|     728576.65 |     3.013 |     73.43 |   0.04343 |
#> |    X|     728576.65 |     3.013 |     73.43 |   0.04343 |
#> |  121|     601355.03 |    -1.210 |     1.431 |     6.615 |
#> |    U|     601355.03 |     2.952 |     71.56 |   0.04807 |
#> |    X|     601355.03 |     2.952 |     71.56 |   0.04807 |
#> |    M|   Mixed Diff. |-1.460e+05 | 6.594e+04 |-1.151e+05 |
#> |  122|     463623.21 |    -1.206 |     1.410 |     8.085 |
#> |    U|     463623.21 |     2.971 |     70.52 |   0.05542 |
#> |    X|     463623.21 |     2.971 |     70.52 |   0.05542 |
#> |    M|   Mixed Diff. |    -8936. | 1.167e+04 |-7.467e+04 |
#> |  123|     317592.94 |    -1.205 |     1.405 |     10.79 |
#> |    U|     317592.94 |     2.977 |     70.23 |   0.06897 |
#> |    X|     317592.94 |     2.977 |     70.23 |   0.06897 |
#> |    M|   Mixed Diff. |     8426. |    -387.3 |-3.840e+04 |
#> |  124|     234743.40 |    -1.204 |     1.404 |     13.66 |
#> |    U|      234743.4 |     2.981 |     70.20 |   0.08330 |
#> |    X|      234743.4 |     2.981 |     70.20 |   0.08330 |
#> |    M|   Mixed Diff. |     5236. |    -1885. |-2.153e+04 |
#> |  125|     176424.77 |    -1.203 |     1.405 |     17.32 |
#> |    U|     176424.77 |     2.987 |     70.26 |    0.1016 |
#> |    X|     176424.77 |     2.987 |     70.26 |    0.1016 |
#> |    M|   Mixed Diff. |     984.2 |    -1908. |-1.165e+04 |
#> |  126|     139065.87 |    -1.201 |     1.408 |     21.63 |
#> |    U|     139065.87 |     2.996 |     70.39 |    0.1232 |
#> |    X|     139065.87 |     2.996 |     70.39 |    0.1232 |
#> |    F| Forward Diff. |    -2306. |    -1588. |    -6360. |
#> |  127|     114599.36 |    -1.199 |     1.412 |     26.82 |
#> |    U|     114599.36 |     3.009 |     70.62 |    0.1491 |
#> |    X|     114599.36 |     3.009 |     70.62 |    0.1491 |
#> |    F| Forward Diff. |    -4826. |    -1257. |    -3438. |
#> |  128|     99625.961 |    -1.195 |     1.418 |     32.62 |
#> |    U|     99625.961 |     3.026 |     70.92 |    0.1781 |
#> |    X|     99625.961 |     3.026 |     70.92 |    0.1781 |
#> |    F| Forward Diff. |    -6614. |    -1000. |    -1903. |
#> |  129|     89536.355 |    -1.191 |     1.427 |     39.83 |
#> |    U|     89536.355 |     3.049 |     71.34 |    0.2142 |
#> |    X|     89536.355 |     3.049 |     71.34 |    0.2142 |
#> |    F| Forward Diff. |    -8084. |    -797.0 |    -997.1 |
#> |  130|     83645.983 |    -1.185 |     1.437 |     47.82 |
#> |    U|     83645.983 |     3.077 |     71.87 |    0.2541 |
#> |    X|     83645.983 |     3.077 |     71.87 |    0.2541 |
#> |    F| Forward Diff. |    -9181. |    -657.6 |    -520.0 |
#> |  131|     80256.503 |    -1.178 |     1.450 |     56.66 |
#> |    U|     80256.503 |     3.111 |     72.50 |    0.2983 |
#> |    X|     80256.503 |     3.111 |     72.50 |    0.2983 |
#> |    M|   Mixed Diff. |-1.002e+04 |    -561.0 |    -259.7 |
#> |  132|     78496.527 |    -1.171 |     1.464 |     65.79 |
#> |    U|     78496.527 |     3.149 |     73.20 |    0.3440 |
#> |    X|     78496.527 |     3.149 |     73.20 |    0.3440 |
#> |    M|   Mixed Diff. |-1.061e+04 |    -496.6 |    -121.4 |
#> |  133|     77694.461 |    -1.163 |     1.478 |     74.47 |
#> |    U|     77694.461 |     3.188 |     73.92 |    0.3874 |
#> |    X|     77694.461 |     3.188 |     73.92 |    0.3874 |
#> |    M|   Mixed Diff. |-1.098e+04 |    -455.3 |    -48.90 |
#> |  134|     77400.400 |    -1.156 |     1.491 |     81.63 |
#> |    U|       77400.4 |     3.223 |     74.57 |    0.4231 |
#> |    X|       77400.4 |     3.223 |     74.57 |    0.4231 |
#> |    M|   Mixed Diff. |-1.114e+04 |    -431.6 |    -12.40 |
#> |  135|     77320.247 |    -1.150 |     1.501 |     86.39 |
#> |    U|     77320.247 |     3.250 |     75.06 |    0.4469 |
#> |    X|     77320.247 |     3.250 |     75.06 |    0.4469 |
#> |    M|   Mixed Diff. |-1.113e+04 |    -421.4 |     4.519 |
#> |  136|     77300.046 |    -1.147 |     1.507 |     88.84 |
#> |    U|     77300.046 |     3.267 |     75.37 |    0.4592 |
#> |    X|     77300.046 |     3.267 |     75.37 |    0.4592 |
#> |    M|   Mixed Diff. |-1.101e+04 |    -420.2 |     11.47 |
#> |  137|     77285.841 |    -1.144 |     1.513 |     90.46 |
#> |    U|     77285.841 |     3.282 |     75.65 |    0.4673 |
#> |    X|     77285.841 |     3.282 |     75.65 |    0.4673 |
#> |    M|   Mixed Diff. |-1.078e+04 |    -424.0 |     15.37 |
#> |  138|     77255.716 |    -1.137 |     1.525 |     92.84 |
#> |    U|     77255.716 |     3.314 |     76.23 |    0.4792 |
#> |    X|     77255.716 |     3.314 |     76.23 |    0.4792 |
#> |    M|   Mixed Diff. |-1.011e+04 |    -440.1 |     20.08 |
#> |  139|     77195.663 |    -1.125 |     1.548 |     95.94 |
#> |    U|     77195.663 |     3.378 |     77.38 |    0.4947 |
#> |    X|     77195.663 |     3.378 |     77.38 |    0.4947 |
#> |    F| Forward Diff. |    -8593. |    -484.9 |     24.29 |
#> |  140|     77094.737 |    -1.103 |     1.587 |     99.04 |
#> |    U|     77094.737 |     3.488 |     79.37 |    0.5102 |
#> |    X|     77094.737 |     3.488 |     79.37 |    0.5102 |
#> |    F| Forward Diff. |    -5695. |    -589.5 |     25.23 |
#> |  141|     76986.984 |    -1.077 |     1.634 |     99.90 |
#> |    U|     76986.984 |     3.617 |     81.70 |    0.5145 |
#> |    X|     76986.984 |     3.617 |     81.70 |    0.5145 |
#> |    F| Forward Diff. |    -1747. |    -759.9 |     19.59 |
#> |  142|     76927.483 |    -1.063 |     1.659 |     97.42 |
#> |    U|     76927.483 |     3.685 |     82.95 |    0.5021 |
#> |    X|     76927.483 |     3.685 |     82.95 |    0.5021 |
#> |    F| Forward Diff. |     1436. |    -903.4 |     9.324 |
#> |  143|     76908.566 |    -1.066 |     1.656 |     94.21 |
#> |    U|     76908.566 |     3.673 |     82.78 |    0.4860 |
#> |    X|     76908.566 |     3.673 |     82.78 |    0.4860 |
#> |    F| Forward Diff. |     2347. |    -923.9 |     1.620 |
#> |  144|     76904.204 |    -1.072 |     1.644 |     92.53 |
#> |    U|     76904.204 |     3.641 |     82.22 |    0.4776 |
#> |    X|     76904.204 |     3.641 |     82.22 |    0.4776 |
#> |    F| Forward Diff. |     1856. |    -874.7 |   -0.7660 |
#> |  145|     76904.204 |    -1.072 |     1.644 |     92.53 |
#> |    U|     76904.204 |     3.641 |     82.22 |    0.4776 |
#> |    X|     76904.204 |     3.641 |     82.22 |    0.4776 |
#> calculating covariance matrix
#> done
#> Calculating residuals/tables
#> done
#> Warning: gradient problems with initial estimate and covariance; see $scaleInfo

# }